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Articles Published Processes
12/6/2019 11:43:25 AM | Browse: 866 | Download: 1310
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Received |
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2019-10-08 04:34 |
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Peer-Review Started |
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2019-10-08 04:35 |
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To Make the First Decision |
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2019-11-15 01:03 |
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Return for Revision |
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2019-11-19 08:33 |
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Revised |
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2019-11-20 07:20 |
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Second Decision |
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2019-11-26 10:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-11-26 17:23 |
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Articles in Press |
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2019-11-26 17:23 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-11-30 03:54 |
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Typeset the Manuscript |
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2019-12-04 12:41 |
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Publish the Manuscript Online |
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2019-12-06 11:43 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Review |
| Article Title |
Overview of organic anion transporters and organic anion transporter polypeptides and their roles in the liver
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ting-Ting Li, Jia-Xing An, Jing-Yu Xu and Bi-Guang Tuo |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Bi-Guang Tuo, MD, PhD, Professor, Department of Gastroenterology, Affiliated Hospital, Zunyi Medical University, 149 Dalian Road, Zunyi 563100, Guizhou Province, China. tuobiguang_gzzy@163.com |
| Key Words |
Organic anion; Substrate transport; Liver fibrosis; Liver cirrhosis; Liver cancer; Targeted therapy |
| Core Tip |
As important anion transporters, organic anion transporters (OATs) and organic anion transporter polypeptides (OATPs) have similar structures and transport substrates. So far, the role of some members of OATs and OATPs in the liver has been reported, but studies on both families are still rare. In this paper, we study the structure, distribution, substrate of action, and its regulatory mechanisms in various diseases of the liver. With the further study of the relationship between OATs/OATPs and various liver diseases, targeted therapy with OATs/OATPs are expected to improve the adverse reactions of drugs in the liver and improve the survival rate of patients with liver diseases. |
| Publish Date |
2019-12-06 11:43 |
| Citation |
Li TT, An JX, Xu JY, Tuo BG. Overview of organic anion transporters and organic anion transporter polypeptides and their roles in the liver. World J Clin Cases 2019; 7(23): 3915-3933 |
| URL |
https://www.wjgnet.com/2307-8960/full/v7/i23/3915.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v7.i23.3915 |
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