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12/6/2019 11:43:25 AM | Browse: 99 | Download: 34
Publication Name World Journal of Clinical Cases
Manuscript ID 51858
Country/Territory China
Received
2019-10-08 04:34
Peer-Review Started
2019-10-08 04:35
To Make the First Decision
2019-11-15 01:03
Return for Revision
2019-11-19 08:33
Revised
2019-11-20 07:20
Second Decision
2019-11-26 10:27
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-11-26 17:23
Articles in Press
2019-11-26 17:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-11-30 03:54
Typeset the Manuscript
2019-12-04 12:41
Publish the Manuscript Online
2019-12-06 11:43
ISSN 2307-8960 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research and Experimental
Manuscript Type Review
Article Title Overview of organic anion transporters and organic anion transporter polypeptides and their roles in the liver
Manuscript Source Invited Manuscript
All Author List Ting-Ting Li, Jia-Xing An, Jing-Yu Xu and Bi-Guang Tuo
ORCID
Author(s) ORCID Number
Ting-Ting Li http://orcid.org/0000-0002-0321-4923
Jia-Xing An http://orcid.org/0000-0002-0988-9972
Jing-Yu Xu http://orcid.org/0000-0002-0545-0444
Bi-Guang Tuo http://orcid.org/0000-0003-3655-6759
Funding Agency and Grant Number
Corresponding author Bi-Guang Tuo, MD, PhD, Professor, Department of Gastroenterology, Affiliated Hospital, Zunyi Medical University, 149 Dalian Road, Zunyi 563100, Guizhou Province, China. tuobiguang_gzzy@163.com
Keywords Organic anion; Substrate transport; Liver fibrosis; Liver cirrhosis; Liver cancer; Targeted therapy
Core Tip As important anion transporters, organic anion transporters (OATs) and organic anion transporter polypeptides (OATPs) have similar structures and transport substrates. So far, the role of some members of OATs and OATPs in the liver has been reported, but studies on both families are still rare. In this paper, we study the structure, distribution, substrate of action, and its regulatory mechanisms in various diseases of the liver. With the further study of the relationship between OATs/OATPs and various liver diseases, targeted therapy with OATs/OATPs are expected to improve the adverse reactions of drugs in the liver and improve the survival rate of patients with liver diseases.
Publish Date 2019-12-06 11:43
Citation Li TT, An JX, Xu JY, Tuo BG. Overview of organic anion transporters and organic anion transporter polypeptides and their roles in the liver. World J Clin Cases 2019; 7(23): 3915-3933
Url https://www.wjgnet.com/2307-8960/full/v7/i23/3915.htm
DOI https://dx.doi.org/10.12998/wjcc.v7.i23.3915
Full Article (PDF) WJCC-7-3915.pdf
Full Article (Word) WJCC-7-3915.docx
Manuscript File 51858-Review_WangTQ.docx
Answering Reviewers 51858-Answering reviewers.pdf
Audio Core Tip 51858-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 51858-Conflict-of-interest statement.pdf
Copyright License Agreement 51858-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 51858-Language certificate.pdf
Peer-review Report 51858-Peer-review(s).pdf
Scientific Misconduct Check 51858-Scientific misconduct check.pdf
Scientific Editor Work List 51858-Scientific editor work list.pdf