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Publication Name World Journal of Gastroenterology
Manuscript ID 52001
Country/Territory China
2019-10-12 10:09
Peer-Review Started
2019-10-12 10:12
To Make the First Decision
Return for Revision
2019-11-27 04:03
2019-12-26 07:38
Second Decision
2019-12-30 05:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-01-01 23:10
Articles in Press
2020-01-01 23:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-01-06 07:59
Typeset the Manuscript
2020-01-11 08:11
Publish the Manuscript Online
2020-01-16 07:58
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Genetics and Heredity
Manuscript Type Case Control Study
Article Title Gene polymorphisms in nucleotide excision repair pathway are associated with colorectal cancer
Manuscript Source Unsolicited Manuscript
All Author List Yan-Ke Li, Qian Xu, Li-Ping Sun, Yue-Hua Gong, Jing-Jing Jing, Cheng-Zhong Xing and Yuan Yuan
Author(s) ORCID Number
Yan-Ke Li http://orcid.org/0000-0003-1114-2963
Qian Xu http://orcid.org/0000-0002-3082-7530
Li-Ping Sun http://orcid.org/0000-0003-1993-8544
Yue-Hua Gong http://orcid.org/0000-0002-0522-624X
Jing-Jing Jing http://orcid.org/0000-0002-9807-8089
Cheng-Zhong Xing http://orcid.org/0000-0001-6463-019X
Yuan Yuan http://orcid.org/0000-0002-7394-9036
Funding Agency and Grant Number
Funding Agency Grant Number
the 13th five years for the National Key Research and Development Program & Key Special Project 2018YFC1311600
Corresponding author Yuan Yuan, PhD, Professor, Tumor Etiology and Screening Department of Cancer Institute and General Surgery, the First Hospital of China Medical University, No.155 NanjingBei Street, Heping District, Shenyang 110001, Liaoning Province, China. yuanyuan@cmu.edu.cn
Keywords Nucleotide excision repair; Polymorphism; Colorectal cancer; Susceptibility; Prognosis;
Core Tip We conducted a two-stage case-control study to explore the association of all tag-single nucleotide polymorphisms (SNPs) in eight nucleotide excision repair pathway genes with colorectal cancer (CRC) risk and prognosis in a northern Chinese population, including a discovery and a validation stages. We newly found two SNPs (XPA rs10817938 and XPC rs2607775) contributed to increased CRC risk in overall and stratification analysis. Another two SNPs (ERCC2 rs1052555 and ERCC5 rs2228959) were also firstly reported to be associated with poor CRC prognosis.
Publish Date 2020-01-16 07:58
Citation Li YK, Xu Q, Sun LP, Gong YH, Jing JJ, Xing CZ, Yuan Y. Gene polymorphisms in nucleotide excision repair pathway are associated with colorectal cancer. World J Gastroenterol 2020; 26(3): 307-323
Url https://www.wjgnet.com/1007-9327/full/v26/i3/307.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i3.307
Full Article (PDF) WJG-26-307.pdf
Full Article (Word) WJG-26-307.docx
Manuscript File 52001-Review_WangTQ.docx
Answering Reviewers 52001-Answering reviewers.pdf
Audio Core Tip 52001-Audio core tip.mp3
Biostatistics Review Certificate 52001-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 52001-Conflict-of-interest statement.pdf
Copyright License Agreement 52001-Review.docx
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 52001-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 52001-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 52001-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 52001-Language certificate.pdf
Supplementary Material 52001-Supplementary material.pdf
Peer-review Report 52001-Peer-review(s).pdf
Scientific Misconduct Check 52001-Scientific misconduct check.pdf
Scientific Editor Work List 52001-Scientific editor work list.pdf