Publication Name	World Journal of Gastroenterology
Manuscript ID	5204
Country	China

Received	2013-08-22 09:44
Peer-Review Started	2013-08-22 20:44
To Make the First Decision	2013-10-14 21:23
Return for Revision	2013-10-19 16:27
Revised	2013-11-14 20:16
Second Decision	2014-01-02 10:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-01-02 12:07
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-02-24 18:18
Typeset the Manuscript	2014-03-03 10:40
Publish the Manuscript Online	2014-03-18 14:14

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Autobiography
Article Title	Mass spectrometry-based serum peptide profiling in hepatocellular carcinoma with bone metastasis
Manuscript Source	Invited Manuscript
All Author List	Jian He, Zhao-Chong Zeng, Zuo-Lin Xiang and Ping Yang
Funding Agency and Grant Number	Funding Agency Grant Number Medical Guidance Program of the Science and Technology Commission of Shanghai Municipality 10411962400
Corresponding Author	Zhao-Chong Zeng, Professor, Department of Radiation Oncology, Zhongshan Hospital, Fudan University, Shanghai 200032, China. zeng.zhaochong@zs-hospital.sh.cn
Key Words	Hepatocellular carcinoma; Serum; Peptides; Matrix-assisted laser desorption ionization-time of flight mass spectrometry; Tumor biomarker
Core Tip	Advances in the diagnosis and treatment of hepatocellular carcinoma (HCC) and extension of overall survival rates have led to an increase in the incidence of bone metastasis of HCC, which accounts for approximately 38.5% of all cases of extrahepatic metastasis of HCC. The patient’s quality of life would significantly be affected by the time of diagnosis. However, early diagnostic molecular markers for bone metastasis from HCC have not yet been identified. In this study, we performed differential serum peptide profiling in HCC patients with bone metastasis, which can be used for early prediction of this disorder.
Publish Date	2014-03-18 14:14
Citation	He J, Zeng ZC, Xiang ZL, Yang P. Mass spectrometry-based serum peptide profiling in hepatocellular carcinoma with bone metastasis. World J Gastroenterol 2014; 20(11): 3025-3032
URL	http://www.wjgnet.com/1007-9327/full/v20/i11/3025.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i11.3025

Full Article (PDF)	WJG-20-3025.pdf
Full Article (Word)	WJG-20-3025.doc
Manuscript File	5204-Review.doc
Answering Reviewers	5204-Answering reviewers.pdf
Copyright License Agreement	5204-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5204-Language certificate.pdf
Peer-review Report	5204-Peer review(s).pdf
Scientific Editor Work List	5204-Scientific editor work list.doc