Category |
Public, Environmental & Occupational Health |
Manuscript Type |
Retrospective Study |
Article Title |
Prevalence, clinical characteristics, risk factors, and indicators for lean Chinese adults with nonalcoholic fatty liver disease
|
Manuscript Source |
Invited Manuscript |
All Author List |
Jing Zeng, Rui-Xu Yang, Chao Sun, Qin Pan, Rui-Nan Zhang, Guang-Yu Chen, Ying Hu and Jian-Gao Fan |
ORCID |
|
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Key Research and Development Plan “Precision Medicine Research” |
2017YFSF090203 |
National Natural Science Foundation of China |
81873565 |
National Natural Science Foundation of China |
81900507 |
Hospital Funded Clinical Research, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine |
17CSK04 |
Hospital Funded Clinical Research, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine |
15LC06 |
|
Corresponding Author |
Jian-Gao Fan, MD, PhD, Professor, Department of Gastroenterology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Children’s Digestion and Nutrition, No. 1665, Kongjiang Road, Yangpu District, Shanghai 200092, China. fanjiangao@xinhuamed.com.cn |
Key Words |
Non-alcoholic fatty liver disease; Lean; Body max index; Waist circumference; Fatty liver index; Triglyceride |
Core Tip |
The precise characterizations of nonalcoholic fatty liver disease (NAFLD) in lean Chinese adults with normal waist circumference (WC) remain unclear. Therefore, we aimed to investigate the prevalence, clinical characterizations, risk factors and possible indicators for NAFLD in this. Among 810 lean participants with normal WC, 142 (17.5%) fulfilled the diagnostic criteria for NAFLD. NAFLD is not uncommon in Chinese lean adults even with normal WC. Metabolic factors may play important roles in this NAFLD rather than genetic factors. A lower cut-off value of the fatty liver index score in screening for NAFLD may be used for Chinese lean adults with normal WC. |
Publish Date |
2020-04-21 06:56 |
Citation |
Zeng J, Yang RX, Sun C, Pan Q, Zhang RN, Chen GY, Hu Y, Fan JG. Prevalence, clinical characteristics, risk factors, and indicators for lean Chinese adults with nonalcoholic fatty liver disease. World J Gastroenterol 2020; 26(15): 1792-1804 |
URL |
https://www.wjgnet.com/1007-9327/full/v26/i15/1792.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v26.i15.1792 |