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Articles Published Processes
9/3/2014 5:47:00 PM | Browse: 1720 | Download: 1808
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Received |
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2013-08-22 10:24 |
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Peer-Review Started |
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2013-08-22 21:24 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2013-10-19 16:53 |
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Revised |
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2013-11-16 01:53 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2013-12-13 13:32 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2013-12-13 14:21 |
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Articles in Press |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-01-14 15:44 |
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Publish the Manuscript Online |
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2014-01-15 10:25 |
| Category |
Oncology |
| Manuscript Type |
Autobiography |
| Article Title |
Novel blood-based microRNA biomarker panel for early diagnosis of pancreatic cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ganepola AP Ganepola, John R Rutledge, Paritosh Suman, Anusak Yiengpruksawan and David H Chang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Valley Hospital Foundation Research Fund |
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| private donations |
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| Corresponding Author |
David H Chang, PhD, Research Scientist, Center for Cancer Research and Genomic Medicine, The Daniel and Gloria Blumenthal Cancer Center, The Valley Hospital, 1 Valley Health Plaza, Paramus, NJ 07652, United States. davidhc9@gmail.com |
| Key Words |
MicroRNA; Diagnosis; Biomarkers; Pancreatic cancer; Blood plasma; Circulating |
| Core Tip |
This study employed high throughput screening as a screening tool to identify blood-based circulating microRNA markers for detection of early stage pancreatic cancer. Two levels of confirmation were performed to ensure the validity of the identified microRNA targets. First, a panel of potential microRNA markers was generated and confirmed using a more specific and sensitive secondary assay, real-time quantitative reverse transcription polymerase chain reaction. Second, the confirmed panel of microRNA markers was independently validated with different experimental procedures and instruments, by independent personnel, and at a different institution, to diagnose a new cohort of patients and controls. |
| Publish Date |
2014-01-15 10:25 |
| Citation |
Ganepola GAP, Rutledge JR, Suman P, Yiengpruksawan A, Chang DH. Novel blood-based microRNA biomarker panel for early diagnosis of pancreatic cancer. World J Gastrointest Oncol 2014; 6(1): 22-33 |
| URL |
http://www.wjgnet.com/1948-5204/full/v6/i1/22.htm |
| DOI |
http://dx.doi.org/10.4251/wjgo.v6.i1.22 |
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