Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	5214
Country	United States

Received	2013-08-22 10:24
Peer-Review Started	2013-08-22 21:24
To Make the First Decision	2013-10-14 14:16
Return for Revision	2013-10-19 16:53
Revised	2013-11-16 01:53
Second Decision	2013-12-13 13:32
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-12-13 14:21
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-01-14 15:44
Publish the Manuscript Online	2014-01-15 10:25

ISSN	1948-5204 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Autobiography
Article Title	Novel blood-based microRNA biomarker panel for early diagnosis of pancreatic cancer
Manuscript Source	Invited Manuscript
All Author List	Ganepola AP Ganepola, John R Rutledge, Paritosh Suman, Anusak Yiengpruksawan and David H Chang
Funding Agency and Grant Number	Funding Agency Grant Number Valley Hospital Foundation Research Fund private donations
Corresponding Author	David H Chang, PhD, Research Scientist, Center for Cancer Research and Genomic Medicine, The Daniel and Gloria Blumenthal Cancer Center, The Valley Hospital, 1 Valley Health Plaza, Paramus, NJ 07652, United States. davidhc9@gmail.com
Key Words	MicroRNA; Diagnosis; Biomarkers; Pancreatic cancer; Blood plasma; Circulating
Core Tip	This study employed high throughput screening as a screening tool to identify blood-based circulating microRNA markers for detection of early stage pancreatic cancer. Two levels of confirmation were performed to ensure the validity of the identified microRNA targets. First, a panel of potential microRNA markers was generated and confirmed using a more specific and sensitive secondary assay, real-time quantitative reverse transcription polymerase chain reaction. Second, the confirmed panel of microRNA markers was independently validated with different experimental procedures and instruments, by independent personnel, and at a different institution, to diagnose a new cohort of patients and controls.
Publish Date	2014-01-15 10:25
Citation	Ganepola GAP, Rutledge JR, Suman P, Yiengpruksawan A, Chang DH. Novel blood-based microRNA biomarker panel for early diagnosis of pancreatic cancer. World J Gastrointest Oncol 2014; 6(1): 22-33
URL	http://www.wjgnet.com/1948-5204/full/v6/i1/22.htm
DOI	http://dx.doi.org/10.4251/wjgo.v6.i1.22

Full Article (PDF)	WJGO-6-22.pdf
Full Article (Word)	WJGO-6-22.doc
Manuscript File	5214-Review.docx
Answering Reviewers	5214-Answering reviewers.pdf
Biostatistics Review Certificate	Biostatistician_Review_Report_20130822030948.pdf
Copyright License Agreement	5214-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethics_Committee_20130822030932.pdf
Peer-review Report	5214-Peer review(s).pdf
Scientific Editor Work List	5214-Scientific editor work list.doc