Publication Name	World Journal of Gastroenterology
Manuscript ID	5221
Country	South Korea

Received	2013-08-23 08:39
Peer-Review Started	2013-08-24 09:24
To Make the First Decision	2013-09-27 16:51
Return for Revision	2013-09-30 11:31
Revised	2013-10-01 22:40
Second Decision	2013-11-13 10:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-11-13 14:40
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-01-22 09:47
Publish the Manuscript Online	2014-03-12 11:24

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	CXC chemokines and chemokine receptors in gastric cancer: From basic findings towards therapeutic targeting
Manuscript Source	Invited Manuscript
All Author List	Hyo Jin Lee, Ik-Chan Song, Hwan-Jung Yun, Deog-Yeon Jo and Samyong Kim
Funding Agency and Grant Number	Funding Agency Grant Number Basic Science Research Program through the National Research of Korea (NRF) funded by the Ministry of Education, Science and Technology NRF-2009-0076540 Basic Science Research Program through the National Research of Korea (NRF) funded by the Ministry of Education, Science and Technology NRF-2009-0067256
Corresponding Author	Deog-Yeon Jo, MD, PhD, Division of Hematology/Oncology, Department of Internal Medicine, School of Medicine Chungnam National University and Chungnam National University Hospital, 640 Daesa-dong, Jung-gu, Daejeon 301-721, South Korea. ggufwhd@naver.com
Key Words	Chemokine; Chemokine receptor; Gastric neoplasm; Therapeutic target
Core Tip	Chemokines were traditionally believed to regulate the directional migration of leukocytes to inflammatory sites. However, it is now clear that chemokines and chemokine receptors also regulate the processes underlying the development and progression of malignant disease. In gastric cancer, CXC chemokines and their receptors directly influence tumorigenesis by modulating tumor transformation, survival, growth, invasion, and metastasis, as well as indirectly by regulating angiogenesis and interactions between tumor and microenvironment. Aim of this review is to discuss the involvement of CXC chemokines and their receptors in the development, progression, and metastasis of gastric cancer and their therapeutic potential.
Publish Date	2014-03-12 11:24
Citation	Lee HJ, Song IC, Yun HJ, Jo DY, Kim S. CXC chemokines and chemokine receptors in gastric cancer: From basic findings towards therapeutic targeting. World J Gastroenterol 2014; 20(7): 1681-1693
URL	http://www.wjgnet.com/1007-9327/full/v20/i7/1681.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i7.1681

Full Article (PDF)	WJG-20-1681.pdf
Full Article (Word)	WJG-20-1681.doc
Manuscript File	5221-Review.doc
Answering Reviewers	5221-Answering reviewers.pdf
Copyright License Agreement	5221-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5221-Language certificate.pdf
Peer-review Report	5221-Peer review(s).pdf
Scientific Editor Work List	5221-Scientific editor work list.doc