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Articles Published Processes
1/13/2020 11:27:13 AM | Browse: 1191 | Download: 2509
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Received |
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2019-11-01 17:35 |
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Peer-Review Started |
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2019-11-01 17:36 |
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First Decision by Editorial Office Director |
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2019-11-22 01:56 |
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Return for Revision |
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2019-11-22 01:56 |
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Revised |
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2019-12-19 22:51 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2019-12-30 07:22 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2020-01-01 22:58 |
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Articles in Press |
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2020-01-01 22:58 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-01-08 02:06 |
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Publish the Manuscript Online |
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2020-01-13 11:27 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Diagnostic and clinical significance of antigen-specific pancreatic antibodies in inflammatory bowel diseases: A meta-analysis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Konstantinos Gkiouras, Maria G Grammatikopoulou, Xenophon Theodoridis, Eirini Pagkalidou, Evangelia Chatzikyriakou, Anna G Apostolidou, Eirini I Rigopoulou, Lazaros I Sakkas and Dimitrios Petrou Bogdanos |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Dimitrios Petrou Bogdanos, MD, PhD, Assistant Professor, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences，University of Thessaly, Biopolis, P.O. Box 1425, Larissa GR41110, Greece. bogdanos@med.uth.gr |
| Key Words |
Inflammatory bowel disease; Gastrointestinal disease; Evidence-based diagnosis; Sensitivity; Specificity; Ulcerative colitis |
| Core Tip |
The majority of individual studies assessing the diagnostic accuracy of autoantibodies for anti-glycoprotein 2 (anti-GP2) for Crohn’s disease (CD) diagnosis either include asymptomatic participants, or patients with symptoms not akin to CD. Most studies carry industry-related conflicts-of-interest, employing non-blinded evaluation of their assays and CD diagnosis preceding anti-GP2 testing. The pooled analyses performed herein using only symptomatic patients as controls, revealed high heterogeneity and low diagnostic accuracy of the anti-GP2, demonstrating low sensitivity and high specificity. Based on the pooled sensitivity and specificity of the anti-GP2 for CD diagnosis, they do not appear to attain the characteristics to be used per se as a proper non-invasive diagnostic tool. |
| Publish Date |
2020-01-13 11:27 |
| Citation |
Gkiouras K, Grammatikopoulou MG, Theodoridis X, Pagkalidou E, Chatzikyriakou E, Apostolidou AG, Rigopoulou EI, Sakkas LI, Bogdanos DP. Diagnostic and clinical significance of antigen-specific pancreatic antibodies in inflammatory bowel diseases: A meta-analysis. World J Gastroenterol 2020; 26(2): 246-265 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i2/246.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i2.246 |
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