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12/30/2019 1:58:17 AM | Browse: 734 | Download: 1346
Publication Name World Journal of Gastrointestinal Pathophysiology
Manuscript ID 52378
Country United States
Received
2019-10-29 20:40
Peer-Review Started
2019-10-29 20:40
To Make the First Decision
2019-11-27 04:12
Return for Revision
2019-11-27 08:27
Revised
2019-12-12 15:53
Second Decision
2019-12-21 06:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-12-23 17:39
Articles in Press
2019-12-23 17:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-12-26 08:04
Publish the Manuscript Online
2019-12-30 01:58
ISSN 2150-5330 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Fecal lactoferrin accurately reflects mucosal inflammation in inflammatory bowel disease
Manuscript Source Invited Manuscript
All Author List Marrieth G Rubio, Kofi Amo-Mensah, James M Gray, Vu Q Nguyen, Sam Nakat, Douglas Grider, Kim Love, James H Boone and Dario Sorrentino
ORCID
Author(s) ORCID Number
Marrieth G Rubio http://orcid.org/0000-0001-7503-2822
Kofi Amo-Mensah http://orcid.org/0000-0001-5440-4957
James M Gray http://orcid.org/0000-0001-6857-9934
Vu Q Nguyen http://orcid.org/0000-0001-7802-8028
Sam Nakat http://orcid.org/0000-0001-6425-1886
Douglas Grider http://orcid.org/0000-0002-6346-094X
Kim Love http://orcid.org/0000-0002-5912-9525
James H Boone http://orcid.org/0000-0002-6839-0944
Dario Sorrentino http://orcid.org/0000-0002-2694-8823
Funding Agency and Grant Number
Corresponding Author Dario Sorrentino, FRACP, MD, Professor, IBD Center - Division of Gastroenterology, Virginia Tech Carilion School of Medicine, 3 Riverside Circle, Roanoke, VA 24018, United States. drsorrentino@carilionclinic.org
Key Words Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis; Fecal lactoferrin; C-reactive protein; White blood cell count
Core Tip Studies have demonstrated a potential role for fecal biomarkers such as fecal calprotectin and fecal lactoferrin (FL) in monitoring Crohn’s disease (CD) and ulcerative colitis (UC). However, their correlation with disease burden (endoscopic scores/disease activity and disease extent) has not been extensively investigated. In our study FL separated disease severity categories based on endoscopic scores in both UC and CD patients. FL showed a close correlation with the diseased mucosal surface and with disease extent and was more closely correlated to endoscopy when determined before endoscopy. FL can accurately and timely represent intestinal inflammation in inflammatory bowel diseases.
Publish Date 2019-12-30 01:58
Citation Rubio MG, Amo-Mensah K, Gray JM, Nguyen VQ, Nakat S, Grider D, Love K, Boone JH, Sorrentino D. Fecal lactoferrin accurately reflects mucosal inflammation in inflammatory bowel disease. World J Gastrointest Pathophysiol 2019; 10(5): 54-63
URL https://www.wjgnet.com/2150-5330/full/v10/i5/54.htm
DOI https://dx.doi.org/10.4291/wjgp.v10.i5.54
Full Article (PDF) WJGP-10-54.pdf
Full Article (Word) WJGP-10-54.docx
STROBE Statement 52378-STROBE-Statement-revision.pdf
Manuscript File 52378-Review.docx
Answering Reviewers 52378-Answering reviewers.pdf
Audio Core Tip 52378-Audio core tip.mp3
Biostatistics Review Certificate 52378-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 52378-Conflict-of-interest statement.pdf
Copyright License Agreement 52378-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 52378-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 52378-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 52378-Institutional review board statement.pdf
Supplementary Material 52378-Supplementary material.pdf
Peer-review Report 52378-Peer-review(s).pdf
Scientific Misconduct Check 52378-Scientific misconduct check.pdf
Scientific Editor Work List 52378-Scientific editor work list.pdf