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Articles Published Processes
12/30/2019 1:58:17 AM | Browse: 853 | Download: 1863
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Received |
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2019-10-29 20:40 |
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Peer-Review Started |
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2019-10-29 20:40 |
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To Make the First Decision |
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2019-11-27 04:12 |
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Return for Revision |
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2019-11-27 08:27 |
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Revised |
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2019-12-12 15:53 |
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Second Decision |
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2019-12-21 06:01 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-12-23 17:39 |
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Articles in Press |
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2019-12-23 17:39 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-12-26 08:04 |
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Publish the Manuscript Online |
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2019-12-30 01:58 |
| ISSN |
2150-5330 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Fecal lactoferrin accurately reflects mucosal inflammation in inflammatory bowel disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Marrieth G Rubio, Kofi Amo-Mensah, James M Gray, Vu Q Nguyen, Sam Nakat, Douglas Grider, Kim Love, James H Boone and Dario Sorrentino |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Dario Sorrentino, FRACP, MD, Professor, IBD Center - Division of Gastroenterology, Virginia Tech Carilion School of Medicine, 3 Riverside Circle, Roanoke, VA 24018, United States. drsorrentino@carilionclinic.org |
| Key Words |
Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis; Fecal lactoferrin; C-reactive protein; White blood cell count |
| Core Tip |
Studies have demonstrated a potential role for fecal biomarkers such as fecal calprotectin and fecal lactoferrin (FL) in monitoring Crohn’s disease (CD) and ulcerative colitis (UC). However, their correlation with disease burden (endoscopic scores/disease activity and disease extent) has not been extensively investigated. In our study FL separated disease severity categories based on endoscopic scores in both UC and CD patients. FL showed a close correlation with the diseased mucosal surface and with disease extent and was more closely correlated to endoscopy when determined before endoscopy. FL can accurately and timely represent intestinal inflammation in inflammatory bowel diseases. |
| Publish Date |
2019-12-30 01:58 |
| Citation |
Rubio MG, Amo-Mensah K, Gray JM, Nguyen VQ, Nakat S, Grider D, Love K, Boone JH, Sorrentino D. Fecal lactoferrin accurately reflects mucosal inflammation in inflammatory bowel disease. World J Gastrointest Pathophysiol 2019; 10(5): 54-63 |
| URL |
https://www.wjgnet.com/2150-5330/full/v10/i5/54.htm |
| DOI |
https://dx.doi.org/10.4291/wjgp.v10.i5.54 |
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