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Articles Published Processes
3/28/2020 1:10:01 PM | Browse: 828 | Download: 1594
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Received |
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2019-12-06 21:47 |
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Peer-Review Started |
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2019-12-06 21:48 |
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To Make the First Decision |
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Return for Revision |
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2020-01-16 22:04 |
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Revised |
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2020-02-21 18:17 |
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Second Decision |
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2020-03-09 15:41 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-03-09 17:47 |
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Articles in Press |
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2020-03-09 17:47 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-03-17 01:23 |
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Typeset the Manuscript |
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2020-03-27 09:18 |
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Publish the Manuscript Online |
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2020-03-28 13:10 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Qingyi decoction protects against myocardial injuries induced by severe acute pancreatitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lei Li, Yong-Qi Li, Zhong-Wei Sun, Cai-Ming Xu, Jun Wu, Ge-Liang Liu, Ahmed MH Bakheet and Hai-Long Chen |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81573751 |
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| Corresponding Author |
Hai-Long Chen, MD, PhD, Chief Doctor, Department of Surgery, The First Affiliated Hospital, Dalian Medical University, No. 222 Zhongshan Road, Dalian 116011, Liaoning Province, China. hailongchen2018@163.com |
| Key Words |
Severe acute pancreatitis; Multiple organs dysfunction; Myocardial injury; Qingyi decoction; STIM1/Orai1-SOCE; |
| Core Tip |
This manuscript illustrates the protecting role of traditional Chinese medicine-Qingyi decoction (QYD) on severe acute pancreatitis-induced myocardial injuries. QYD treatment is able to play a double roles as a preventive and curative agent for both myocardial injuries and acute severe pancreatitis via the STIM1/Orai1-SOCE pathway. The QYD treatment reduced myocardial injuries and mortality rate by 30% among the SD rats within 24 h. Our findings reveal the success of QYD on improving the overall appearance of SD rats, together with decreasing the myocardial histological abnormalities and inflammatory cells infiltration caused by the severe acute pancreatitis and myocardial injury diseases. |
| Publish Date |
2020-03-28 13:10 |
| Citation |
Li L, Li YQ, Sun ZW, Xu CM, Wu J, Liu GL, Bakheet AMH, Chen HL. Qingyi decoction protects against myocardial injuries induced by severe acute pancreatitis. World J Gastroenterol 2020;26(12): 1317-1328 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i12/1317.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i12.1317 |
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