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Articles Published Processes
4/15/2020 12:00:00 PM | Browse: 874 | Download: 1954
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Received |
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2019-11-07 10:40 |
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Peer-Review Started |
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2019-11-07 10:40 |
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To Make the First Decision |
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Return for Revision |
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2019-12-05 18:55 |
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Revised |
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2020-02-27 09:33 |
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Second Decision |
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2020-03-19 10:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-03-22 21:36 |
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Articles in Press |
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2020-03-22 21:36 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-04-14 01:36 |
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Publish the Manuscript Online |
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2020-04-15 12:00 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Methodology |
| Manuscript Type |
Evidence-Based Medicine |
| Article Title |
Adjuvant chemotherapy in curatively resected rectal cancer: How valid are the data?
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Giulia Manzini, Fabius Hapke, Ian N Hines, Doris Henne-Bruns and Michael Kremer |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Giulia Manzini, MD, MSc, Doctor, Doctor, Surgeon, Department of General and Visceral Surgery, University of Ulm, Albert-Einstein-Allee 23, Ulm 89081, Germany. giulia.manzini@uniklinik-ulm.de |
| Key Words |
Rectal cancer; Validity; Meta-analysis; CONSORT checklist; Postoperative chemotherapy; Overall survival |
| Core Tip |
The role of adjuvant chemotherapy (CTx) in curatively resected rectal cancer needs to be considered cautiously. Petersen et al. published a Cochrane review in 2012 which found an improvement in survival in patients receiving adjuvant CTx after surgery in comparison to those who were treated by surgery only. The result was based on 21 studies, 5 of them supporting the advantage of CTx. Among these, we selected the three most powerful studies and assessed their validity, which was poor. Surprisingly, our meta-analysis without these studies yielded similar results as the original study (still in favor of adjuvant CTx). |
| Publish Date |
2020-04-15 12:00 |
| Citation |
Manzini G, Hapke F, Hines IN, Henne-Bruns D, Kremer M. Adjuvant chemotherapy in curatively resected rectal cancer: How valid are the data? World J Gastrointest Oncol 2020; 12(4): 503-513 |
| URL |
https://www.wjgnet.com/1948-5204/full/v12/i4/503.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v12.i4.503 |
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