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Articles Published Processes
2/21/2020 12:51:51 AM | Browse: 778 | Download: 1185
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Received |
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2019-11-18 06:15 |
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Peer-Review Started |
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2019-11-18 06:15 |
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To Make the First Decision |
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Return for Revision |
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2019-12-23 16:11 |
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Revised |
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2020-01-07 01:21 |
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Second Decision |
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2020-01-09 11:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-01-11 14:07 |
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Articles in Press |
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2020-01-11 14:07 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-01-19 01:50 |
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Typeset the Manuscript |
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2020-02-12 10:37 |
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Publish the Manuscript Online |
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2020-02-21 00:51 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Role of Tenascin-X in regulating the TGF-β/Smad signaling pathway in the pathogenesis of slow transit constipation
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi-Chao Zhang, Bao-Xiang Chen, Cong-Qing Jiang, Xiao-Yu Xie, Yan Zhou and Qun Qian |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Cong-Qing Jiang, PhD, Professor, Surgeon, Colorectal Surgery Department, Zhongnan Hosptial of Wuhan University, No. 169 East Lake Road, Wuchang District, Wuhan 430071, Hubei Province, China. wb002554@whu.edu.cn |
| Key Words |
Slow transit constipation; Tenascin-X; Extracellular matrix glycoproteins; TGF-β; ; |
| Core Tip |
There are couplers of results in this paper may be found interested by the general readers. The extracellular matrix protein Tenascin-X may activate the TGF-β/Smad signaling pathway by upregulating the Smad2/3 signaling protein and thereby induce slight or complete epithelial stromal cell transformation, leading to an abnormal distribution and dysfunction of interstitial cells of Cajal in the diseased colon, which promotes the occurrence and development of slow transit constipation. |
| Publish Date |
2020-02-21 00:51 |
| Citation |
Zhang YC, Chen BX, Xie XY, Zhou Y, Qian Q, Jiang CQ. Role of Tenascin-X in regulating the TGF-β/Smad signaling pathway in the pathogenesis of slow transit constipation. World J Gastroenterol 2020; 26(7): 717-724 |
| URL |
https://www.wjgnet.com/2219-2840/full/v26/i7/717.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i7.717 |
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