| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Technetium-99m-labeled macroaggregated albumin lung perfusion scan for diagnosis of hepatopulmonary syndrome: A prospective study comparing brain uptake and whole-body uptake
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
He Zhao, Jiaywei Tsauo, Xiao-Wu Zhang, Huai-Yuan Ma, Ning-Na Weng, Gong-Shun Tang and Xiao Li |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Key R and D Program of China |
2017YFC0107800 |
| CAMS Initiative for Innovative Medicine |
2016-12M-2-004 |
|
| Corresponding Author |
Xiao Li, MD, PhD, Doctor, Doctor, Postdoc, Professor, Department of Interventional Therapy, National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. simonlixiao@gmail.com |
| Key Words |
Portal Hypertension; Intrapulmonary Vascular Dilations; Radionuclide Imaging; Technetium-99m-labeled Macroaggregated albumin Lung Perfusion Scan; Diagnostic Tests; Sensitivity and Specificity |
| Core Tip |
Hepatopulmonary syndrome is a common complication of liver disease which impairs the lungs’ ability to oxygenate blood, leading to debilitating symptoms, such as shortness of breath. Intrapulmonary vascular dilations, a hallmark of hepatopulmonary syndrome, can be detected using technetium-99m-labeled macroaggregated albumin lung perfusion scan, however, of the two most commonly used methods of result interpretation (i.e., brain uptake and whole-body uptake), it is unclear which is more accurate. In this study of 69 patients with liver cirrhosis, we found that whole-body uptake is more accurate than brain uptake for detecting intrapulmonary vascular dilations. |
| Publish Date |
2020-03-14 15:03 |
| Citation |
Zhao H, Tsauo J, Zhang X, Ma H, Weng N, Tang G, Li X. Technetium-99m-labeled macroaggregated albumin lung perfusion scan for diagnosis of hepatopulmonary syndrome: A prospective study comparing brain uptake and whole-body uptake. World J Gastroenterol 2020; 26(10): 1088-1097 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i10/1088.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i10.1088 |
