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Articles Published Processes
4/6/2020 7:54:48 AM | Browse: 848 | Download: 1374
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Received |
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2019-11-15 08:39 |
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Peer-Review Started |
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2019-11-15 08:40 |
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To Make the First Decision |
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Return for Revision |
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2020-02-20 23:32 |
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Revised |
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2020-03-20 08:44 |
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Second Decision |
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2020-03-26 12:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-03-26 21:14 |
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Articles in Press |
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2020-03-26 21:14 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-04-03 12:07 |
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Publish the Manuscript Online |
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2020-04-06 07:54 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Case Report |
| Article Title |
Acute myeloid leukemia with t(11;19)(q23;p13.1) in a patient with a gastrointestinal stromal tumor undergoing imatinib therapy: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hong Jun Kim, Sun Kyung Baek, Chi Hoon Maeng, Si-Young Kim, Tae Sung Park and Jae Joon Han |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jae Joon Han, MD, PhD, Professor, Department of Hematology and Medical oncology, Kyung Hee University, Kyungheedae-Ro 23, Dongdaemoon-Gu, Seoul 02447, South Korea. anemia@khu.ac.kr |
| Key Words |
Acute myeloid leukemia; Gastrointestinal stromal tumor; Imatinib; KMT2A; Myelodysplastic syndrome; Case report |
| Core Tip |
To the best of our knowledge, this is the first report of acute myeloid leukemia with KMT2A gene rearrangements in a patient with a gastrointestinal stromal tumor receiving imatinib mesylate (IM) treatment. Although there is no known mechanism by which IM causes acute leukemia, there have been reports supporting the speculation that IM may have a direct mutagenic effect on normal hematopoietic precursors. Physicians should consider the potential risks of developing hematologic malignancies, including therapy-related acute myeloid leukemia, in patients with gastrointestinal stromal tumors receiving IM treatment. |
| Publish Date |
2020-04-06 07:54 |
| Citation |
Kim HJ, Baek SK, Maeng CH, Kim SY, Park TS, Han JJ. Acute myeloid leukemia with t(11;19)(q23;p13.1) in a patient with a gastrointestinal stromal tumor undergoing imatinib therapy: A case report. World J Clin Cases 2020; 8(7): 1251-1256 |
| URL |
https://www.wjgnet.com/2307-8960/full/v8/i7/1251.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v8.i7.1251 |
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