Publication Name	World Journal of Gastroenterology
Manuscript ID	528
Country	Brazil

Received	2012-09-14 22:07
Peer-Review Started	2012-09-17 14:19
To Make the First Decision	2012-11-21 15:48
Return for Revision	2012-11-22 09:12
Revised	2012-12-19 04:26
Second Decision	2013-01-11 16:32
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-01-12 02:14
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-03-27 09:00
Publish the Manuscript Online	2013-04-09 16:03

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Noninvasive methods for prediction of esophageal varices in pediatric patients with portal hypertension
Manuscript Source	Invited Manuscript
All Author List	Marina Rossato Adami, Cristina Targa Ferreira, Carlos Oscar Kieling, Vania Hirakata and Sandra Maria Gonçalves Vieira
Funding Agency and Grant Number	Funding Agency Grant Number FIPE-HCPA (Research and Events Support Fund at Hospital de Clínicas de Porto Alegre)
Corresponding Author	Dr. Marina Rossato Adami, Universidade Federal do Rio Grande do Sul, Post-Graduation in Gastroenterology and Hepatology, Hospital de Clínicas de Porto Alegre, Pediatric Gastroenterology Unit, Porto Alegre, Rio Grande do Sul 91350-170, Brasil. marinaadami2008@gmail.com
Key Words	Portal hypertension; Clinical predictors; Pediatric patients; Esophageal varices
Core Tip	Children with portal hypertension (PH) are at risk for variceal bleeding. The standard test for screening varices is endoscopy, an invasive method. We evaluated non-invasive markers for diagnosing esophageal varices (EV) in 103 children (95% intrahepatic PH). All patients had no bleeding history and underwent endoscopy for EV screening. Platelet count (< 115 000), clinical prediction rule (< 114) and risk score (cutoff > -1.2) were the best predictors of EV. Limitations are the retrospective design and the small number of pre-hepatic PH patients. The strength is the paucity of pediatric studies related to this issue and the assessment of risk score in children.
Publish Date	2013-04-09 16:03
Citation	Adami MR, Ferreira CT, Kieling CO, Hirakata V, Vieira SMG. Noninvasive methods for prediction of esophageal varices in pediatric patients with portal hypertension. World J Gastroenterol 2013; 19(13): 2053-2059
URL	http://www.wjgnet.com/1007-9327/full/v19/i13/2053.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i13.2053

Full Article (PDF)	WJG-19-2053.pdf
Manuscript File	528-Review.doc
Answering Reviewers	528-Answering Reviewers.doc
Biostatistics Review Certificate	statistical review report.pdf
Copyright License Agreement	528-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	ethical approvement.pdf
Non-Native Speakers of English Editing Certificate	528-Language certificate.pdf
Peer-review Report	528-Peer review(s).docx
Scientific Editor Work List	528-Scientific editor work list.doc