Publication Name	World Journal of Gastroenterology
Manuscript ID	5285
Country	United States

Received	2013-08-28 10:34
Peer-Review Started	2013-08-28 14:05
To Make the First Decision	2013-09-16 20:23
Return for Revision	2013-09-18 08:35
Revised	2013-09-29 08:29
Second Decision	2013-10-17 14:33
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-10-18 07:51
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-11-18 11:40
Publish the Manuscript Online	2013-12-18 09:53

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Immunology
Manuscript Type	Topic Highlights
Article Title	Role of innate immunity in the development of hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Rajagopal N Aravalli
Funding Agency and Grant Number
Corresponding Author	Rajagopal N Aravalli, PhD, Department of Radiology, University of Minnesota Medical School, MMC 292, Mayo Memorial Building, 420 Delaware Street S.E., Minneapolis, MN 55455, United States. arava001@umn.edu
Key Words	Hepatocellular carcinoma; Innate immunity; Toll-like receptor; Liver cancer; Inflammation
Core Tip	Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. Growing incidence of HCC has generated immense interest to understand the mechanisms of disease at the physiological, cellular and molecular levels with the hope of developing novel therapeutics for the treatment of HCC. In the past few years, it has become clear that innate immunity plays a critical role in the development and progression of HCC. In this review, these new developments and possibilities of developing novel therapeutic options based on this newly gained knowledge are discussed.
Publish Date	2013-12-18 09:53
Citation	Aravalli RN. Role of innate immunity in the development of hepatocellular carcinoma. World J Gastroenterol 2013; 19(43): 7500-7514
URL	http://www.wjgnet.com/1007-9327/full/v19/i43/7500.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i43.7500

Full Article (PDF)	WJG-19-7500.pdf
Manuscript File	5285-Review.doc
Answering Reviewers	5285-Answering reviewers.pdf
Copyright License Agreement	5285-Copyright assignment.pdf
Peer-review Report	5285-Peer review(s).pdf
Scientific Editor Work List	5285-Scientific editor work list.doc