Publication Name	World Journal of Gastroenterology
Manuscript ID	52978
Country	China

Received	2019-11-30 17:27
Peer-Review Started	2019-11-30 17:28
To Make the First Decision
Return for Revision	2020-01-16 22:34
Revised	2020-02-17 23:58
Second Decision	2020-03-04 12:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-03-05 07:17
Articles in Press	2020-03-05 07:17
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-03-19 20:39
Typeset the Manuscript	2020-04-06 09:20
Publish the Manuscript Online	2020-04-07 14:46

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Preoperative gamma-glutamyltransferase to lymphocyte ratio predicts long-term outcomes in intrahepatic cholangiocarcinoma patients following hepatic resection
Manuscript Source	Unsolicited Manuscript
All Author List	Jin-Ju Wang, Hui Li, Jia-Xin Li, Lin Xu, Hong Wu and Yong Zeng
ORCID	Author(s) ORCID Number Jin-Ju Wang http://orcid.org/0000-0003-1210-7676 Hui Li http://orcid.org/0000-0001-7287-2690 Jia-Xin Li http://orcid.org/0000-0002-6264-283X Lin Xu http://orcid.org/0000-0002-1595-5622 Hong Wu http://orcid.org/0000-0001-5397-4800 Yong Zeng http://orcid.org/0000-0002-7846-963X
Funding Agency and Grant Number	Funding Agency Grant Number National Key Technologies RD Program 2018YFC1106803 Natural Science Foundation of China 81972747 Natural Science Foundation of China 81770615 Natural Science Foundation of China 81872004 Natural Science Foundation of China 81672882 Science and Technology Support Program of Sichuan Province 2019YFQ0001 Science and Technology Support Program of Sichuan Province 2017SZ0003
Corresponding Author	Yong Zeng, MD, PhD, Doctor, Professor, Surgeon, Department of Liver Surgery and Liver Transplantation Center, West China Hospital of Sichuan University, Guoxuexiang No. 37, Chengdu 610041, Sichuan Province, China. zengyong@medmail.com.cn
Key Words	Gamma-glutamyltransferase; Lymphocyte ratio; Gamma-glutamyltransferase to lymphocyte ratio; Intrahepatic cholangiocarcinoma; Prognosis; Survival analysis
Core Tip	This study aimed to investigate the clinical significance of preoperative gamma-glutamyltransferase to lymphocyte ratio (GLR) levels in intrahepatic cholangiocarcinoma (ICC) patients following hepatectomy. We retrospectively enrolled 527 ICC patients underwent curative hepatectomy at our center. The results showed that a higher GLR is associated with worse overall survival and recurrence-free survival in ICC patients after hepatectomy. Thus, the preoperative GLR is an independent prognostic factor for ICC patients following curative resection.
Publish Date	2020-04-07 14:46
Citation	Wang JJ, Li H, Li JX, Xu L, Wu H, Zeng Y. Preoperative gamma-glutamyltransferase to lymphocyte ratio predicts long-term outcomes in intrahepatic cholangiocarcinoma patients following hepatic resection. World J Gastroenterol 2020; 26(13): 1501-1512
URL	https://www.wjgnet.com/1007-9327/full/v26/i13/1501.htm
DOI	https://dx.doi.org/10.3748/wjg.v26.i13.1501

Full Article (PDF)	WJG-26-1501.pdf
Full Article (Word)	WJG-26-1501.docx
Manuscript File	52978-Review-Filipodia.docx
Answering Reviewers	52978-Answering reviewers.pdf
Audio Core Tip	52978-Audio core tip.m4a
Biostatistics Review Certificate	52978-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	52978-Conflict-of-interest statement.pdf
Copyright License Agreement	52978-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	52978-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	52978-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	52978-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	52978-Language certificate.pdf
Supplementary Material	52978-Supplementary material.pdf
Peer-review Report	52978-Peer-review(s).pdf
Scientific Misconduct Check	52978-Scientific misconduct check.pdf
Scientific Editor Work List	52978-Scientific editor work list.pdf