Publication Name	World Journal of Gastroenterology
Manuscript ID	5307
Country	China

Received	2013-08-29 08:32
Peer-Review Started	2013-08-29 15:24
To Make the First Decision	2013-09-27 16:47
Return for Revision	2013-09-29 16:31
Revised
Second Decision	2014-01-08 18:19
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-08 18:34
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-01-23 17:45
Typeset the Manuscript	2014-02-19 15:51
Publish the Manuscript Online	2014-02-26 11:18

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Leptomeningeal carcinomatosis as the initial manifestation of gastric adenocarcinoma: A case report
Manuscript Source	Invited Manuscript
All Author List	Jian-Wen Guo, Xiao-Tian Zhang, Xiao-Sheng Chen, Xin-Chun Zhang, Guang-Juan Zheng, Bei-Ping Zhang and Ye-Feng Cai
Funding Agency and Grant Number	Funding Agency Grant Number Research Fund for the Doctoral Program of Higher Education of China 20104425120009
Corresponding Author	Ye-Feng Cai, Professsor, Brain Centre, Guangdong Province Hospital of Traditional Chinese Medicine, Guangzhou University of Traditional Chinese Medicine, No. 111 Dade Road, Yuexiu District, Guangzhou 510120, Guangdong Province, China. jianwen_guo@qq.com
Key Words	meningeal carcinomatosis; stomach neoplasms; endoscopes; gastrointestinal; spinal puncture; cytological techniques; pathology; clinical
Core Tip	Here we report on a patient, initially and alone, presented with neurological symptoms and signs without any clues indicating gastric cancer. Evidence shows that the tumor directly spread solely to the brain without involvement of any other organs or tissues. How do we make an accurate and rapid diagnosis? cerebral spinal fluid cytological studies play a key role in diagnosis, finding malignant cells that originate from epithelial cells. A gastroscopic examination was performed, revealing a tumor in the gastric antrum which was classified as Bormann type?Ⅰ?in macroscopic appearance, a rare type in Bormann classification, however, with poor differentiation in pathology. This patient survived for 4 mo without treatment. It is unclear whether this particular form of metastasis affects clinical outcomes.
Publish Date	2014-02-26 11:18
Citation	Guo JW, Zhang XT, Chen XS, Zhang XC, Zheng GJ, Zhang BP, Cai YF. Leptomeningeal carcinomatosis as the initial manifestation of gastric adenocarcinoma: A case report. World J Gastroenterol 2014; 20(8): 2120-2126
URL	http://www.wjgnet.com/1007-9327/full/v20/i8/2120.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i8.2120

Full Article (PDF)	WJG-20-2120.pdf
Full Article (Word)	WJG-20-2120.doc
Manuscript File	5307-Review.doc
Answering Reviewers	5307-Answering reviewers.pdf
Copyright License Agreement	5307-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5307-Language certificate.pdf
Peer-review Report	5307-Peer review(s).pdf
Scientific Editor Work List	5307-Scientific editor work list.doc