Publication Name	World Journal of Gastroenterology
Manuscript ID	53110
Country	Canada

Received	2019-12-06 01:35
Peer-Review Started	2019-12-06 01:36
To Make the First Decision
Return for Revision	2020-02-16 22:00
Revised	2020-02-21 17:04
Second Decision	2020-03-04 12:26
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2020-03-05 06:56
Articles in Press	2020-03-05 06:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-03-19 06:01
Publish the Manuscript Online	2020-03-21 02:52

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Landscape of BRIP1 molecular lesions in gastrointestinal cancers from published genomic studies
Manuscript Source	Invited Manuscript
All Author List	Ioannis A Voutsadakis
ORCID	Author(s) ORCID Number Ioannis A Voutsadakis http://orcid.org/0000-0002-9301-5951
Funding Agency and Grant Number
Corresponding Author	Ioannis A Voutsadakis, MD, PhD, Assistant Professor, Doctor, Doctor, Algoma District Cancer Program, Sault Area Hospital, 750 Great Northern Road, Sault Ste Marie ON P6B 0A8, Canada. ivoutsadakis@yahoo.com
Key Words	BRIP1; FANCJ; BACH1; Gastrointestinal cancers; Mutations; Copy number alterations
Core Tip	BRIP1 gene alterations are uncommon in gastrointestinal cancers. Mutations frequently occur in hypermutated carcinomas and co-occur with other homologous recombination genes mutations. Despite their rarity, BRIP1 defects may present an opportunity for therapeutic interventions similar to other homologous recombination defects.
Publish Date	2020-03-21 02:52
Citation	Voutsadakis JA. Landscape of BRIP1 molecular lesions in gastrointestinal cancers from published genomic studies. World J Gastroenterol 2020; 26(11): 1197-1207
URL	https://www.wjgnet.com/1007-9327/full/v26/i11/1197.htm
DOI	https://dx.doi.org/10.3748/wjg.v26.i11.1197

Full Article (PDF)	WJG-26-1197.pdf
Full Article (Word)	WJG-26-1197.docx
Manuscript File	53110-Review.docx
Answering Reviewers	53110-Answering reviewers.pdf
Audio Core Tip	53110-Audio core tip.wma
Biostatistics Review Certificate	53110-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	53110-Conflict-of-interest statement.pdf
Copyright License Agreement	53110-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	53110-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	53110-Institutional review board statement.pdf
Peer-review Report	53110-Peer-review(s).pdf
Scientific Misconduct Check	53110-Scientific misconduct check.pdf
Scientific Editor Work List	53110-Scientific editor work list.pdf
CrossCheck Report	53110-CrossCheck report.pdf