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4/7/2020 2:46:34 PM | Browse: 1101 | Download: 2505
Publication Name World Journal of Gastroenterology
Manuscript ID 53145
Country Spain
Received
2019-12-08 16:20
Peer-Review Started
2019-12-08 16:20
First Decision by Editorial Office Director
2020-01-19 19:10
Return for Revision
2020-01-19 19:10
Revised
2020-03-06 08:30
Publication Fee Transferred
Second Decision by Editor
2020-03-18 11:00
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2020-03-19 01:00
Articles in Press
2020-03-19 01:00
Edit the Manuscript by Language Editor
2020-03-27 01:48
Typeset the Manuscript
2020-04-06 00:56
Publish the Manuscript Online
2020-04-07 14:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Evaluation of 177Lu-Dotatate treatment in patients with metastatic neuroendocrine tumors and prognostic factors
Manuscript Source Unsolicited Manuscript
All Author List Estephany Abou Jokh Casas, Virginia Pubul Núñez, Urbano Anido-Herranz, Maria del Carmen Mallón Araujo, Maria del Carmen Pombo Pasín, Miguel Garrido Pumar, José Manuel Cabezas Agrícola, José Manuel Cameselle-Teijeiro, Ashraf Hilal and Álvaro Ruibal Morell
ORCID
Author(s) ORCID Number
Estephany Abou Jokh Casas http://orcid.org/0000-0003-0193-828X
Virginia Pubul Núñez http://orcid.org/0000-0002-4717-197X
Urbano Anido-Herranz http://orcid.org/0000-0003-0376-5642
Maria del Carmen Mallón Araujo http://orcid.org/0000-0001-5136-1592
Maria del Carmen Pombo Pasín http://orcid.org/0000-0003-1347-0629
Miguel Garrido Pumar http://orcid.org/0000-0003-2093-1286
José Manuel Cabezas Agrícola http://orcid.org/0000-0003-4616-0512
José Manuel Cameselle-Teijeiro http://orcid.org/0000-0002-5516-8914
Ashraf Hilal http://orcid.org/0000-0002-4580-4366
Álvaro Ruibal Morell http://orcid.org/0000-0002-6001-547X
Funding Agency and Grant Number
Corresponding Author Estephany Abou Jokh Casas, MD, Occupational Physician, Department of Nuclear Medicine, Santiago de Compostela´s University Hospital, Avenida Choupana, Santiago de Compostela 15706, A Coruña, Spain. estephanyaboujokh@gmail.com
Key Words Peptide receptor radionuclide therapy; Gastropancreatic neuroendocrine tumors; Radiological response; Metabolic response; ;
Core Tip Peptide receptor radionuclide therapy has been used successfully in patients diagnosed with metastatic gastroenteropancreatic somatostatin receptor positive tumors when cytoreductive options are limited. In this study we found that overall survival was inversely proportional to toxicity to previous treatments and directly proportional to matching lesion findings between octreoscan and computed tomography pre-peptide receptor radionuclide therapy, tumor grade, bone metastasis and primary tumor and metastasis surgery. Also, that pseudo-progression in the middle of the treatment was a common finding that should be taken into consideration by clinicians in daily practice.
Publish Date 2020-04-07 14:46
Citation Abou Jokh Casas E, Pubul V, Anido-Herranz U, Mallón M, Pombo M, Garrido M, Cabezas JM, Cameselle JM, Hilal A, Ruibal Á. Evaluation of 177Lu-Dotatate treatment in patients with metastatic neuroendocrine tumors and prognostic factors. World J Gastroenterol 2020; 26(13): 1513-1524
URL https://www.wjgnet.com/1007-9327/full/v26/i13/1513.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i13.1513
Full Article (PDF) WJG-26-1513.pdf
Full Article (Word) WJG-26-1513.docx