9/15/2014 9:25:00 AM | Browse: 879 | Download: 959
Publication Name | World Journal of Transplantation |
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Manuscript ID | 5319 |
Country | China |
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2013-12-31 17:17 |
ISSN | 2220-3230 (online) |
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Open Access | |
Copyright | |
Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website | http://www.wjgnet.com |
Category | Transplantation | ||||
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Manuscript Type | Review | ||||
Article Title | Optimal stem cell source for allogeneic stem cell transplantation for hematological malignancies | ||||
Manuscript Source | Invited Manuscript | ||||
All Author List | Daniel KL Cheuk | ||||
Funding Agency and Grant Number |
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Corresponding Author | Daniel KL Cheuk, FHKAM, Department of Paediatrics and Adolescent Medicine, the University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, China. cheukkld@hkucc.hku.hk | ||||
Key Words | Hematopoietic stem cell transplantation; Bone marrow; Peripheral blood stem cell; Cord blood; Hematological malignancy | ||||
Core Tip | Core tip: Randomized controlled trials (RCTs) suggest no difference in survival between peripheral blood stem cell (PBSC) and bone marrow (BM) in matched sibling transplant for patients with hematological malignancies. PBSC may result in fewer relapse in high risk patients but more severe graft-versus-host disease (GVHD). For unrelated donor, the only RCT suggests PBSC and BM result in comparable survivals, with PBSC resulting in fewer graft failure but more chronic GVHD. RCT is not available to compare cord blood with BM or PBSC. The risks and benefits of different sources of stem cells likely change with transplant methods and manipulation of grafts. | ||||
Publish Date | 2013-12-31 17:17 | ||||
Citation | Cheuk DKL. Optimal stem cell source for allogeneic stem cell transplantation for hematological malignancies. World J Transplant 2013; 3(4): 99-112 | ||||
URL | http://www.wjgnet.com/2220-3230/full/v3/i4/99.htm | ||||
DOI | http://dx.doi.org/10.5500/wjt.v3.i4.99 |
Full Article (PDF) | WJT-3-99.pdf |
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Full Article (Word) | WJT-3-99.doc |
Manuscript File | 5319-Review.doc |
Answering Reviewers | 5319-Answering reviewers.pdf |
Copyright License Agreement | 5319-Copyright assignment.pdf |
Peer-review Report | 5319-Peer review(s).pdf |
Scientific Editor Work List | 5319-Scientific editor work list.doc |