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Publication Name World Journal of Transplantation
Manuscript ID 5319
Country China
Received
2013-08-29 09:19
Peer-Review Started
2013-08-29 16:39
To Make the First Decision
2013-09-09 14:29
Return for Revision
2013-09-11 11:06
Revised
2013-11-15 23:27
Second Decision
2013-12-10 16:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-12-11 09:13
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-12-25 17:11
Publish the Manuscript Online
2013-12-31 17:17
ISSN 2220-3230 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Review
Article Title Optimal stem cell source for allogeneic stem cell transplantation for hematological malignancies
Manuscript Source Invited Manuscript
All Author List Daniel KL Cheuk
Funding Agency and Grant Number
Funding Agency Grant Number
University of Hong Kong
Corresponding Author Daniel KL Cheuk, FHKAM, Department of Paediatrics and Adolescent Medicine, the University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, China. cheukkld@hkucc.hku.hk
Key Words Hematopoietic stem cell transplantation; Bone marrow; Peripheral blood stem cell; Cord blood; Hematological malignancy
Core Tip Core tip: Randomized controlled trials (RCTs) suggest no difference in survival between peripheral blood stem cell (PBSC) and bone marrow (BM) in matched sibling transplant for patients with hematological malignancies. PBSC may result in fewer relapse in high risk patients but more severe graft-versus-host disease (GVHD). For unrelated donor, the only RCT suggests PBSC and BM result in comparable survivals, with PBSC resulting in fewer graft failure but more chronic GVHD. RCT is not available to compare cord blood with BM or PBSC. The risks and benefits of different sources of stem cells likely change with transplant methods and manipulation of grafts.
Publish Date 2013-12-31 17:17
Citation Cheuk DKL. Optimal stem cell source for allogeneic stem cell transplantation for hematological malignancies. World J Transplant 2013; 3(4): 99-112
URL http://www.wjgnet.com/2220-3230/full/v3/i4/99.htm
DOI http://dx.doi.org/10.5500/wjt.v3.i4.99
Full Article (PDF) WJT-3-99.pdf
Full Article (Word) WJT-3-99.doc
Manuscript File 5319-Review.doc
Answering Reviewers 5319-Answering reviewers.pdf
Copyright License Agreement 5319-Copyright assignment.pdf
Peer-review Report 5319-Peer review(s).pdf
Scientific Editor Work List 5319-Scientific editor work list.doc