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Articles Published Processes
4/28/2020 8:04:30 AM | Browse: 746 | Download: 1312
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Received |
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2020-01-18 09:21 |
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Peer-Review Started |
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2020-01-18 09:21 |
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To Make the First Decision |
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Return for Revision |
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2020-02-27 05:10 |
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Revised |
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2020-02-29 12:25 |
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Second Decision |
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2020-04-03 12:52 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-04-04 02:51 |
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Articles in Press |
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2020-04-04 02:51 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-04-14 01:30 |
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Typeset the Manuscript |
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2020-04-27 05:59 |
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Publish the Manuscript Online |
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2020-04-28 08:04 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
Mutation analysis of related genes in hamartoma polyps tissue of Peutz-Jeghers syndrome
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhi Zhang, Fu-Xiao Duan, Guo-Li Gu and Peng-Fei Yu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Major Projects of the Chinese PLA "Thirteenth Five-Year Plan" Logistics Research Subject |
AKJ15J003 |
| Major Projects of the Chinese PLA "Thirteenth Five-Year Plan" Logistics Research Subject |
AKJ15J001 |
| Incubation Project of Military Medical Science and Technology Youth Cultivation Program |
17QNP023 |
| Beijing Capital Medical Development Research Fund |
Zhuan20200131 |
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| Corresponding Author |
Guo-Li Gu, MD, MSc, Assistant Professor, Chief Doctor, Department of General Surgery, Air Force Medical Center, PLA; Air Force Clinical College (Air Force Medical Center) of Anhui Medical University, No. 30 Fucheng Road, Haidian District, Beijing 100142, China. kzggl@163.com |
| Key Words |
Peutz-Jeghers syndrome; STK11 gene; LKB1 gene; Sequencing; Genetic analysis; |
| Core Tip |
Peutz-Jeghers syndrome (PJS) is currently considered as an autosomal dominant inherited disease caused by germline mutations of LKB1/STK11 gene. Gastrointestinal hamartoma polyps are one of the most common clinical manifestations. In order to investigate the mutation status of these familiar genetically-related genes in PJS hamartoma polyps tissues, high-throughput sequencing was used to analyze the mutations of related genes in PJS hamartoma polyps. In addition, the relationship between the mutation status and the clinical pathological data of PJS were discussed. |
| Publish Date |
2020-04-28 08:04 |
| Citation |
Zhang Z, Duan FX, Gu GL, Yu PF. Mutation analysis of related genes in hamartoma polyps tissue of Peutz-Jeghers syndrome. World J Gastroenterol 2020; 26(16): 1926-1937 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i16/1926.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i16.1926 |
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