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3/26/2020 3:19:09 AM | Browse: 838 | Download: 1972
Publication Name World Journal of Clinical Cases
Manuscript ID 53207
Country China
Received
2019-12-10 08:42
Peer-Review Started
2019-12-10 08:43
To Make the First Decision
Return for Revision
2019-12-30 12:01
Revised
2020-01-07 12:54
Second Decision
2020-03-04 12:04
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2020-03-05 06:54
Articles in Press
2020-03-05 06:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-03-08 23:59
Typeset the Manuscript
2020-03-20 09:34
Publish the Manuscript Online
2020-03-26 03:19
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Clinical characteristics and 28-d outcomes of bacterial infections in patients with hepatitis B virus-related acute-on-chronic liver failure
Manuscript Source Invited Manuscript
All Author List Chen Li, Hai-Bin Su, Xiao-Yan Liu and Jin-Hua Hu
ORCID
Author(s) ORCID Number
Chen Li http://orcid.org/0000-0003-2370-7255
Hai-Bin Su http://orcid.org/0000-0002-7958-5974
Xiao-Yan Liu http://orcid.org/0000-0002-9237-2201
Jin-Hua Hu http://orcid.org/0000-0002-0804-912X
Funding Agency and Grant Number
Funding Agency Grant Number
innovation projects of The Fifth Medical Center of Chinese PLA General Hospital YNKT2014007
Corresponding Author Hai-Bin Su, MD, MPhil, Doctor, Doctor, Liver Failure Treatment and Research Center, The Fifth Medical Center of Chinese PLA General Hospital, No. 100 West Fourth Ring Road, Beijing 100039, China. suhaibin302@163.com
Key Words Hepatitis B virus; Acute-on-chronic liver failure; Bacterial infections; Outcomes; Chronic liver disease; Spontaneous bacterial peritonitis
Core Tip Bacterial infections (BIs) play pivotal roles in the deterioration of clinical course in patients with acute-on-chronic liver failure (ACLF). This study aimed to investigate the clinical characteristics of first BIs in patients with hepatitis B virus-ACLF, as defined by the Chinese Group on the Study of Severe Hepatitis B. Healthcare-associated and nosocomial BIs were the most common types. Pneumonia was the most common site of BIs. Gram-negative bacteria accounted for 83.6%, and multidrug-resistant organisms accounted for 29.5% of bacteria detected. The 28-d transplant-free survival rates of the patients were very low. Chinese Group on the Study of Severe Hepatitis B-ACLF score, acute kidney injury, bloodstream infection, prothrombin activity, and invasive catheter were the independent predictors of 28-d outcomes.
Publish Date 2020-03-26 03:19
Citation Li C, Su HB, Liu XY, Hu JH. Clinical characteristics and 28-d outcomes of bacterial infections in patients with hepatitis B virus-related acute-on-chronic liver failure. World J Clin Cases 2020; 8(6): 1042-1055
URL https://www.wjgnet.com/2307-8960/full/v8/i6/1042.htm
DOI https://dx.doi.org/10.12998/wjcc.v8.i6.1042
Full Article (PDF) WJCC-8-1042.pdf
Full Article (Word) WJCC-8-1042.docx
Manuscript File 53207-Review_WangTQ.docx
Answering Reviewers 53207-Answering reviewers.pdf
Audio Core Tip 53207-Audio core tip.mp3
Biostatistics Review Certificate 53207-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 53207-Conflict-of-interest statement.pdf
Copyright License Agreement 53207-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 53207-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 53207-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 53207-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 53207-Language certificate.pdf
Peer-review Report 53207-Peer-review(s).pdf
Scientific Misconduct Check 53207-Scientific misconduct check.pdf
Scientific Editor Work List 53207-Scientific editor work list.pdf
CrossCheck Report 53207-CrossCheck report.pdf