Publication Name	World Journal of Gastroenterology
Manuscript ID	5321
Country	Greece

Received	2013-08-29 09:27
Peer-Review Started	2013-08-29 16:47
To Make the First Decision	2013-09-27 16:46
Return for Revision	2013-09-29 14:31
Revised	2013-10-25 07:08
Second Decision	2013-11-01 16:58
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-11-03 11:41
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-12-12 15:03
Publish the Manuscript Online	2014-01-20 16:41

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Hepatocellular carcinoma in chronic hepatitis B patients under antiviral therapy
Manuscript Source	Invited Manuscript
All Author List	John Vlachogiannakos and George Papatheodoridis
Funding Agency and Grant Number
Corresponding Author	George Papatheodoridis, MD, Academic Department of Gastroenterology, Athens University Medical School, Laiko General Hospital, Agiou Thoma 17, 11527 Athens, Greece. gepapath@med.uoa.gr
Key Words	Chronic hepatitis B; Hepatocellular carcinoma; Interferon; Lamivudine; Adefovir; Entecavir; Tenofovir; Virological remission; Cirrhosis
Core Tip	Antiviral therapy reduces but does not eliminate the risk of hepatocellular carcinoma (HCC) in chronic hepatitis B patients with or without cirrhosis. The reduction of the HCC incidence under a high genetic barrier nucleos(t)ide analogue is higher in the vast majority of patients who will achieve virological remission compared to those who may maintain detectable viral replication. In current clinical practice, however, patients at increased baseline HCC risk should continue to undergo HCC surveillance according to the existing recommendations even if they have achieved complete long-term inhibition of viral replication and improvements in liver histology.
Publish Date	2014-01-20 16:41
Citation	Vlachogiannakos J, Papatheodoridis G. Hepatocellular carcinoma in chronic hepatitis B patients under antiviral therapy. World J Gastroenterol 2013; 19(47): 8822-8830
URL	http://www.wjgnet.com/1007-9327/full/v19/i47/8822.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i47.8822

Full Article (PDF)	WJG-19-8822.pdf
Manuscript File	5321-Review.doc
Answering Reviewers	5321-Answering Reviewers.pdf
Copyright License Agreement	5321-Copyright Assignment.pdf
Peer-review Report	5321-Peer Review(s).pdf
Scientific Editor Work List	5321-Scientific editor work list.doc