BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/11/2020 9:58:04 AM | Browse: 943 | Download: 1137
 |
Received |
|
2019-12-27 14:06 |
|
Peer-Review Started |
|
2019-12-27 14:10 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2020-01-28 20:56 |
|
Revised |
|
2020-02-10 18:04 |
|
Second Decision |
|
2020-03-19 09:52 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2020-03-22 21:19 |
|
Articles in Press |
|
2020-03-22 21:19 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2020-04-26 01:42 |
|
Publish the Manuscript Online |
|
2020-05-11 09:58 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Genetics & Heredity |
| Manuscript Type |
Review |
| Article Title |
Shared (epi)genomic background connecting neurodegenerative diseases and type 2 diabetes
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Valerio Caputo, Andrea Termine, Claudia Strafella, Emiliano Giardina and Raffaella Cascella |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Emiliano Giardina, PhD, Associate Professor, Molecular Genetics Laboratory UILDM, Santa Lucia Foundation, Via Ardeatina 354, Rome 00142, Italy. emiliano.giardina@uniroma2.it |
| Key Words |
Type 2 diabetes; Alzheimer’s disease; Parkinson’s disease; Metabolism; Neurodegeneration; Neuroinflammation; Genetic variants; Epigenomic background; Disease interactome |
| Core Tip |
Populations’ progressive aging raises important challenges to be faced, including the increased prevalence of metabolic, neurodegenerative and movement disorders, especially of type 2 diabetes, Alzheimer’s disease and Parkinson’s disease. These disorders are characterized by a multifactorial etiology, involving genetic and non-genetic factors, which may overlap. This review will discuss the shared (epi)genomic features, the role of mutually-associated genetic variants, common gene expression profiles and epigenetic background leading to development and progression of such disorders. Overall, this review highlights the importance of characterizing the “disease interactome” in order to establish adequate personalized and preventative healthcare approaches for the ageing populations. |
| Publish Date |
2020-05-11 09:58 |
| Citation |
Caputo V, Termine A, Strafella C, Giardina E, Cascella R. Shared (epi)genomic background connecting neurodegenerative diseases and type 2 diabetes. World J Diabetes 2020; 11(5): 155-164 |
| URL |
https://www.wjgnet.com/1948-9358/full/v11/i5/155.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v11.i5.155 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
