Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	53290
Country	Brazil

Received	2019-12-15 22:02
Peer-Review Started	2019-12-15 22:02
First Decision by Editorial Office Director	2020-04-02 22:04
Return for Revision	2020-04-02 22:04
Revised	2020-04-10 05:33
Publication Fee Transferred
Second Decision by Editor	2020-04-29 12:21
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2020-05-05 15:25
Articles in Press	2020-05-05 15:25
Edit the Manuscript by Language Editor	2020-05-13 02:57
Typeset the Manuscript	2020-06-15 09:30
Publish the Manuscript Online	2020-06-19 09:46

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Role of micronutrients in staging of nonalcoholic fatty liver disease: A retrospective cross-sectional study
Manuscript Source	Invited Manuscript
All Author List	Franciele Sabadin Bertol, Bruna Araujo, Brunno Brochado Jorge, Natalino Rinaldi, Luiz Alberto De Carli and Cristiane Valle Tovo
ORCID	Author(s) ORCID Number Franciele Sabadin Bertol http://orcid.org/0000-0002-8568-0265 Bruna Araujo http://orcid.org/0000-0002-9443-9924 Brunno Brochado Jorge http://orcid.org/0000-0001-6897-5566 Natalino Rinaldi http://orcid.org/0000-0001-9584-0798 Luiz Alberto De Carli http://orcid.org/0000-0001-8875-9908 Cristiane Valle Tovo http://orcid.org/0000-0002-7932-5937
Funding Agency and Grant Number
Corresponding Author	Cristiane Valle Tovo, MD, PhD, Adjunct Professor, Assistant Professor, Graduate Program of Medicine: Hepatology, Universidade Federal de Ciências da Saúde de Porto Alegre, Rua Sarmento Leite 245, Porto Alegre 90430080, RS, Brazil. cristianev@ufcspa.edu.br
Key Words	Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Liver cirrhosis; Micronutrients; Vitamin D; Vitamin B12
Core Tip	Nonalcoholic fatty liver disease presents high incidence throughout the world, and micronutrients may be involved in the pathophysiology of the disease. This study evaluated the relationship between serum levels of micronutrients and severity of nonalcoholic fatty liver disease. Six hundred and fourteen patients undergoing bariatric surgery that had serum levels of micronutrients (vitamin D, vitamin B12, zinc, iron and magnesium) assessed in preoperative period were included. Vitamin D level was negatively correlated with severity of steatosis and nonalcoholic steatohepatitis, and vitamin B12 level was positively correlated with severity of steatosis and fibrosis. In conclusion, vitamin D and vitamin B12 are related to the severity of steatosis, nonalcoholic steatohepatitis and liver fibrosis.
Publish Date	2020-06-19 09:46
Citation	Bertol FS, Araujo B, Jorge BB, Rinaldi N, De Carli LA, Tovo CV. Role of micronutrients in staging of nonalcoholic fatty liver disease: A retrospective cross-sectional study. World J Gastrointest Surg 2020; 12(6): 269-276
URL	https://www.wjgnet.com/1948-9366/full/v12/i6/269.htm
DOI	https://dx.doi.org/10.4240/wjgs.v12.i6.269

Full Article (PDF)	WJGS-12-269.pdf
Full Article (Word)	WJGS-12-269.docx