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Articles Published Processes
11/25/2020 2:44:03 PM | Browse: 512 | Download: 1167
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Received |
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2020-01-01 13:06 |
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Peer-Review Started |
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2020-01-01 13:07 |
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To Make the First Decision |
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Return for Revision |
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2020-09-29 20:01 |
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Revised |
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2020-10-05 15:02 |
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Second Decision |
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2020-10-16 11:31 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-10-20 04:04 |
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Articles in Press |
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2020-10-20 04:04 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-10-25 19:07 |
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Typeset the Manuscript |
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2020-11-18 00:42 |
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Publish the Manuscript Online |
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2020-11-25 14:44 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Hematology |
| Manuscript Type |
Case Report |
| Article Title |
CLAG-M chemotherapy followed by umbilical cord blood stem cell transplantation for primary refractory acute myeloid leukaemia in a child: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jie Huang, Xiao-Yun Yang, Liu-Cheng Rong, Yao Xue, Jun Zhu and Yong-Jun Fang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81670155 |
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| Corresponding Author |
Yong-Jun Fang, MD, PhD, Chief Doctor, Dean, Hematology and Oncology, Children's Hospital of Nanjing Medical University, No. 72, Guangzhou Road, Nanjing 210008, Jiangsu Province, China. fyj322@189.cn |
| Key Words |
Acute myeloid leukaemia; CLAG-M protocol; Salvage therapy; Refractory; Child; Case report |
| Core Tip |
The outcome of refractory and/or relapsed acute myeloid leukemia (R/R AML) in childhood remains poor. We presented herein, a boy with primary refractory AML achieved complete remission (CR) after being treated with one cycle of the CLAG-M protocol as salvage therapy. Umbilical cord blood stem cell transplantation was carried out after CR. The patient remains in complete remission without previous genetic abnormalities. The CLAG-M protocol might be an effective and tolerable salvage regimen and a bridge to haematopoietic stem cell transplantation in R/R AML in childhood. Additionally, we focussed our literature review on the role of cladribine-based protocols in paediatric and adult R/R AML patients. |
| Publish Date |
2020-11-25 14:44 |
| Citation |
Huang J, Yang XY, Rong LC, Xue Y, Zhu J, Fang YJ. CLAG-M chemotherapy followed by umbilical cord blood stem cell transplantation for primary refractory acute myeloid leukaemia in a child: A case report. World J Clin Cases 2020; 8(22): 5603-5610 |
| URL |
https://www.wjgnet.com/2307-8960/full/v8/i22/5603.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v8.i22.5603 |
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