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Articles Published Processes
6/6/2020 2:43:56 PM | Browse: 941 | Download: 1560
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Received |
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2019-12-30 19:28 |
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Peer-Review Started |
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2019-12-30 19:29 |
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To Make the First Decision |
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Return for Revision |
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2020-01-13 17:18 |
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Revised |
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2020-03-27 12:27 |
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Second Decision |
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2020-05-25 09:50 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-05-26 02:38 |
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Articles in Press |
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2020-05-26 02:38 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-06-03 08:14 |
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Publish the Manuscript Online |
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2020-06-06 14:43 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Gut microbiome in primary sclerosing cholangitis: A review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Rebecca Little, Eytan Wine, Binita M Kamath, Anne M Griffiths and Amanda Ricciuto |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Amanda Ricciuto, FRCPC, MD, PhD, Assistant Professor, Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, 555 University Avenue, Toronto ON M5G1X8, Canada. amanda.ricciuto@sickkids.ca |
| Key Words |
Bile acids; Colitis; Inflammatory bowel disease; Microbiome; Microbiota; Primary sclerosing cholangitis |
| Core Tip |
The frequent coexistence of primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) points to the gut-liver axis as central to pathogenesis. The gut microbiome is hypothesized to be involved. A growing body of literature supports that PSC and PSC-IBD are associated with a distinct gut microbiome and more recent animal studies suggest a potential causal relationship. Microbial metabolites, such as bile acids, may mediate the effects of the gut microbiota in PSC. A sound understanding of the PSC microbiome has the potential to inform the development of microbe-altering therapeutic interventions. |
| Publish Date |
2020-06-06 14:43 |
| Citation |
Little R, Wine E, Kamath BM, Griffiths AM, Ricciuto A. Gut microbiome in primary sclerosing cholangitis: A review. World J Gastroenterol 2020; 26(21): 2768-2780 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i21/2768.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i21.2768 |
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