Publication Name	World Journal of Biological Chemistry
Manuscript ID	5337
Country	China

Received	2013-09-02 07:19
Peer-Review Started	2013-09-02 15:33
To Make the First Decision	2013-10-28 16:09
Return for Revision	2013-10-29 10:48
Revised	2013-11-09 11:57
Second Decision	2013-12-19 12:58
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-12-19 13:15
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-12-24 22:48
Typeset the Manuscript	2014-02-26 11:18
Publish the Manuscript Online	2014-03-19 21:35

ISSN	1949-8454 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Review
Article Title	Roles and mechanisms of the CD38/cyclic adenosine diphosphate ribose/Ca2+ signaling pathway
Manuscript Source	Invited Manuscript
All Author List	Wenjie Wei, Richard Graeff and Jianbo Yue
Funding Agency and Grant Number	Funding Agency Grant Number Research Grant Council 782709M Research Grant Council 785911M Research Grant Council 769912M Research Grant Council 785213M
Corresponding Author	Jianbo Yue, PhD, Department of Physiology, the University of Hong Kong, 102 Pok Fu Lam Road, Hong Kong, China. jbyue@me.com
Key Words	Cyclic adenosine diphosphate ribose; CD38; Ca2+; Ryanodine receptors; Nicotinamide adenine dinucleotide
Core Tip	This is a comprehensive review regarding the role and mechanism of the CD38/Cyclic adenosine diphosphate ribose (cADPR)/Ca2+ signaling pathway in various cellular processes. We introduce the structure and function of cADPR, together with its production and degradation pathways. We also describe CD38, the main enzyme that is responsible for synthesis of cADPR, through its structure and topology. Finally, we summarize the functions of the CD38/cADPR/Ca2+ signaling pathway under both physiological and pathological conditions.
Publish Date	2014-03-19 21:35
Citation	Wei W, Graeff R, Yue J. Roles and mechanisms of the CD38/cyclic adenosine diphosphate ribose/Ca2+ signaling pathway. World J Biol Chem 2014; 5(1): 58-67 Available from: URL: http://www.wjgnet.com/1949-8454/full/v5/i1/58.htm DOI: http://dx.doi.org/10.4331/wjbc.v5.i1.58
URL	http://www.wjgnet.com/1949-8454/full/v5/i1/58.htm
DOI	http://dx.doi.org/10.4331/wjbc.v5.i1.58

Full Article (PDF)	wjbc-5-58.pdf
Full Article (Word)	wjbc-5-58.doc
Manuscript File	5337-Review.docx
Answering Reviewers	5337-Answering reviewers.pdf
Copyright License Agreement	5337-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5337-Language certificate.pdf
Peer-review Report	5337-Peer review(s).pdf
Scientific Editor Work List	5337-Scientific editor work list.doc