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Articles Published Processes
5/14/2020 10:35:45 AM | Browse: 936 | Download: 1384
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Received |
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2019-12-17 10:19 |
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Peer-Review Started |
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2019-12-17 10:20 |
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To Make the First Decision |
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Return for Revision |
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2020-02-20 05:33 |
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Revised |
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2020-03-26 07:46 |
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Second Decision |
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2020-03-27 07:26 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-03-30 01:43 |
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Articles in Press |
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2020-03-30 01:43 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-04-17 02:31 |
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Publish the Manuscript Online |
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2020-05-14 10:35 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Free fatty acids receptors 2 and 3 control cell proliferation by regulating cellular glucose uptake
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Saeed Al Mahri, Amal Al Ghamdi, Maaged Akiel, Monira Al Aujan, Sameer Mohammad and Mohammad Azhar Aziz |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mohammad Azhar Aziz, BSc, MSc, PhD, Research Scientist, Colorectal Cancer Research Program, King Abdullah International Medical Research Center, P.O. Box 3660, Riyadh 11426, Saudi Arabia. azizmo@ngha.med.sa |
| Key Words |
Cell proliferation; Glucose transporter 1; Colorectal cancer; Free fatty acids receptor 2; Free fatty acids receptor 3; Glucose uptake |
| Core Tip |
Free fatty acid receptors (FFAR) have been reported to be associated with colorectal cancer (CRC). In this report, we studied short chain FFAR2 and FFAR3 and have provided preliminary evidence about the possible involvement of increased glucose uptake in FFAR2 and FFAR3 knockdown clones of CRC cell line. We generated double knock down for FFAR2 and FFAR3 genes in a CRC cell line (HCT116) and studied possible mechanisms of increased cell proliferation in these cells. |
| Publish Date |
2020-05-14 10:35 |
| Citation |
Al Mahri S, Al Ghamdi A, Akiel M, Al Aujan M, Mohammad S, Aziz MA. Free fatty acids receptors 2 and 3 control cell proliferation by regulating cellular glucose uptake. World J Gastrointest Oncol 2020; 12(5): 514-525 |
| URL |
https://www.wjgnet.com/1948-5204/full/v12/i5/514.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v12.i5.514 |
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