Publication Name	World Journal of Cardiology
Manuscript ID	5350
Country	Thailand

Received	2013-09-02 07:45
Peer-Review Started	2013-09-02 17:17
To Make the First Decision	2013-09-17 09:30
Return for Revision	2013-09-17 21:24
Revised
Second Decision	2013-10-18 10:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-10-18 11:56
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-11-18 11:44
Publish the Manuscript Online	2013-12-04 08:54

ISSN	1949-8462 (online)
Open Access
Copyright
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Minireviews
Article Title	Taurine supplementation in spontaneously hypertensive rats: Advantages and limitations for human applications
Manuscript Source	Invited Manuscript
All Author List	Atchariya Suwanich, J Michael Wyss and Sanya Roysommuti
Funding Agency and Grant Number	Funding Agency Grant Number National Center for Complementary and Alternative Medicine and the National Institutes of Health (NIH) Office of Dietary Supplements 5P50 AT-00477 NIH Neuroscience Blueprint Mouse Phenotyping Core at University of Alabama at Birmingham P30 NS-057098 Faculty of Medicine, Khon Kaen University, Thailand to J Michael Wyss
Corresponding Author	Sanya Roysommuti, PhD, Department of Physiology, Faculty of Medicine, Khon Kaen University, 123 Mitraparp Road, Muang District, Khon Kaen 40002, Thailand. sanya@kku.ac.th
Key Words	Arterial pressure; Circadian rhythm; Hypertension; Spontaneously hypertensive rat; NaCl; Taurine
Core Tip	Many reports indicate that dietary taurine can reduce hypertension in humans and in animal models; however, the hypotensive effect of taurine supplementation depends on many factors. Taurine supplementation improves hypertension in spontaneously hypertensive rats on a low salt diet but fails to attenuate hypertension on a high salt diet. In humans, some epidemiologic studies suggest that people with high taurine and low salt diets display lower arterial pressure than those with low taurine and high salt diets. This review considers both positive and negative effects of taurine on blood pressure in animal models of hypertension to apply for human interventions.
Publish Date	2013-12-04 08:54
Citation	Suwanich A, Wyss JM, Roysommuti S. Taurine supplementation in spontaneously hypertensive rats: Advantages and limitations for human applications. World J Cardiol 2013; 5(11): 404-409
URL	http://www.wjgnet.com/1949-8462/full/v5/i11/404.htm
DOI	http://dx.doi.org/10.4330/wjc.v5.i11.404

Full Article (PDF)	WJC-5-404.pdf
Manuscript File	5350-Review.docx
Answering Reviewers	5350-Answering reviewers.pdf
Copyright License Agreement	5350-Copyright assignment.pdf
Peer-review Report	5350-Peer review(s).pdf
Scientific Editor Work List	5350-Scientific editor work list.doc