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Articles Published Processes
6/6/2020 2:43:56 PM | Browse: 958 | Download: 1542
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Received |
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2020-01-04 23:29 |
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Peer-Review Started |
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2020-01-04 23:29 |
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To Make the First Decision |
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Return for Revision |
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2020-02-24 22:44 |
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Revised |
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2020-03-27 16:43 |
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Second Decision |
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2020-05-27 06:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-05-28 03:04 |
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Articles in Press |
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2020-05-28 03:04 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-06-03 02:15 |
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Publish the Manuscript Online |
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2020-06-06 14:43 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
M2BPGi for assessing liver fibrosis in patients with hepatitis C treated with direct-acting antivirals
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| Manuscript Source |
Invited Conference Manuscripts |
| All Author List |
Shereen A Saleh, Mohamed M Salama, Marwan M Alhusseini and Ghada A Mohamed |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ghada A Mohamed, MD, Lecturer, Gastroenterology and Hepatology Unit, Department of Internal Medicine, Faculty of Medicine, Ain Shams University, Khalifa El-Maamon St., Abbassia, Cairo 11341, Egypt. ghadaabdelrahman@med.asu.edu.eg |
| Key Words |
Hepatitis C virus; Liver fibrosis; Human Mac-2 binding protein; Antiviral agents; Sustained virologic response; Elastography |
| Core Tip |
For 12 wk, 80 chronic hepatitis C patients received a sofosbuvir/daclatasvir/± ribavirin treatment. All patients achieved sustained virologic response (SVR12). Serum Mac-2 binding protein glycosylation isomer (M2BPGi) levels, liver stiffness measurements, fibrosis-4 (FIB-4) and PAPAS index decreased significantly at SVR12. At baseline, M2BPGi was the best marker to distinguish patients with grade F4 fibrosis, patients with grade F2 from grade F0-1 fibrosis, patients with grade F3-4 from grade F0-2 fibrosis, and patients with grade F2-4 from grade F0-1 fibrosis. At SVR12, M2BPGi had the greatest AUCs for differentiating patients with grade F4 fibrosis, patients with grade F3 from grade F0-2 fibrosis, patients with grade F3-4 from grade F0-2 fibrosis, and patients with grade F2-4 from grade F0-1 fibrosis. |
| Publish Date |
2020-06-06 14:43 |
| Citation |
Saleh SA, Salama MM, Alhusseini MM, Mohamed GA. M2BPGi for assessing liver fibrosis in patients with hepatitis C treated with direct-acting antivirals. World J Gastroenterol 2020; 26(21): 2864-2876 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i21/2864.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i21.2864 |
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