Publication Name	World Journal of Cardiology
Manuscript ID	5363
Country	Japan

Received	2013-09-03 10:00
Peer-Review Started	2013-09-03 14:17
To Make the First Decision	2013-11-12 14:31
Return for Revision	2013-11-12 16:57
Revised	2013-11-16 11:47
Second Decision	2014-03-04 09:53
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-04 10:18
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-19 17:28
Typeset the Manuscript	2014-04-23 08:14
Publish the Manuscript Online	2014-04-24 19:19

ISSN	1949-8462 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Topic Highlights
Article Title	Myocardial ischemia is a key factor in the management of stable coronary artery disease
Manuscript Source	Invited Manuscript
All Author List	Kohichiro Iwasaki
Funding Agency and Grant Number
Corresponding Author	Kohichiro Iwasaki, MD, Department of Cardiology, Okayama Kyokuto Hospital, 567-1 Kurata, Naka-ku, Okayama 703-8265, Japan. kiwasaki@kyokuto.or.jp
Key Words	Coronary artery bypass surgery; Coronary revascularization; Fractional flow reserve; Myocardial ischemia; Myocardial perfusion imaging; Percutaneous coronary intervention
Core Tip	Studies of myocardial perfusion imaging demonstrate that, for patients with moderate to severe ischemia, revascularization is the preferred therapy for survival benefit. For patients with no to mild ischemia, medical therapy is the main choice, and revascularization is associated with increased mortality probably because of worsened ischemia. Studies using fractional flow reserve demonstrate that ischemia-guided percutaneous coronary intervention (PCI) is superior to angiography-guided PCI, and the presence of ischemia is the key factor in decision-making for PCI. Thus, myocardial ischemia is a key factor in the management of patients with stable coronary artery disease.
Publish Date	2014-04-24 19:19
Citation	Iwasaki K. Myocardial ischemia is a key factor in the management of stable coronary artery disease. World J Cardiol 2014; 6(4): 130-139
URL	http://www.wjgnet.com/1949-8462/full/v6/i4/130.htm
DOI	http://dx.doi.org/10.4330/wjc.v6.i4.130

Full Article (PDF)	WJC-6-130.pdf
Full Article (Word)	WJC-6-130.doc
Manuscript File	5363-Review.doc
Answering Reviewers	5363-Answering reviewers.pdf
Copyright License Agreement	5363-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5363-Language certificate.pdf
Peer-review Report	5363-Peer review(s).pdf
Scientific Editor Work List	5363-Scientific editor work list.doc