| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Functionality is not an independent prognostic factor for pancreatic neuroendocrine tumors
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hong-Yu Chen, Ya-Liang Zhou, Yong-Hua Chen, Xing Wang, Hao Zhang, Neng-Wen Ke, Xu-Bao Liu and Chun-Lu Tan |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| 1.3.5 Project for Disciplines of Excellence, West China Hospital, Sichuan University, China |
ZY2017302 1-3-5 |
| Key Research and Development Projects of Sichuan Province |
2017SZ0132 |
| Key Research and Development Projects of Sichuan Province |
2019YFS0042 |
|
| Corresponding Author |
Chun-Lu Tan, MD, Associate Professor, Department of Pancreatic Surgery, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Wuhou District, Chengdu 610041, Sichuan Province, China. chunlutan@163.com |
| Key Words |
Neuroendocrine tumors; Pancreatic neoplasms; Prognosis; Paraneoplastic endocrine syndromes; Multivariate analysis; Neoplasm staging |
| Core Tip |
Pancreatic neuroendocrine tumors (pNETs) are classified into functional tumors and nonfunctional tumors according to the existence of hormones related symptoms. The traditional view is that the functionality is correlated with prognosis of pNET patients, which remains a controversial opinion. In this study, we retrospectively analyzed the clinicopathological data of 426 patients from the Surveillance, Epidemiology, and End Results database and 205 patients from the West China Hospital database. The results indicated that the functionality is not associated with prognosis. Race, age, sex and T stage are independent factors for predicting the survival of patients with pNET. |
| Publish Date |
2020-07-07 14:50 |
| Citation |
Chen HY, Zhou YL, Chen YH, Wang X, Zhang H, Ke NW, Liu XB, Tan CL. Functionality is not an independent prognostic factor for pancreatic neuroendocrine tumors. World J Gastroenterol 2020; 26(25): 3638-3649 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i25/3638.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i25.3638 |
