Publication Name	World Journal of Gastroenterology
Manuscript ID	53658
Country	Japan

Received	2019-12-27 11:06
Peer-Review Started	2019-12-27 11:12
To Make the First Decision
Return for Revision	2020-02-14 17:43
Revised	2020-03-27 11:36
Second Decision	2020-05-22 09:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2020-05-23 01:04
Articles in Press	2020-05-23 01:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-06-04 07:44
Publish the Manuscript Online	2020-06-06 14:43

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Website	http://www.wjgnet.com

Category	Immunology
Manuscript Type	Review
Article Title	Vaccine therapy for dysbiosis-related diseases
Manuscript Source	Invited Manuscript
All Author List	Kosuke Fujimoto and Satoshi Uematsu
ORCID	Author(s) ORCID Number Kosuke Fujimoto http://orcid.org/0000-0002-2948-549X Satoshi Uematsu http://orcid.org/0000-0002-5347-6737
Funding Agency and Grant Number	Funding Agency Grant Number Ministry of Education, Culture, Sports, Science, and Technology of Japan (Grant-in-Aid for Early-Career Scientists) 19K17932
Corresponding Author	Satoshi Uematsu, MD, PhD, Professor, Department of Immunology and Genomics, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan. uematsu.satoshi@med.osaka-cu.ac.jp
Key Words	Dysbiosis; IgA; Microbiome; Mucosal immunity; Pathobiont; Vaccine
Core Tip	How to control intestinal pathogenic bacteria that mediate multifactorial diseases is a major concern worldwide. There are few methods for controlling only intestinal pathogenic bacteria; therefore, we have developed a prime–boost type, next-generation mucosal vaccine, and have used it for control of bacterial intestinal diseases. This vaccine can contribute to prevention of Clostridium ramosum-mediated obesity. Thus, this approach might be useful for protecting against microbe-associated disorders of the intestine.
Publish Date	2020-06-06 14:43
Citation	Fujimoto K, Uematsu S. Vaccine therapy for dysbiosis-related diseases. World J Gastroenterol 2020; 26(21): 2758-2767
URL	https://www.wjgnet.com/1007-9327/full/v26/i21/2758.htm
DOI	https://dx.doi.org/10.3748/wjg.v26.i21.2758

Full Article (PDF)	WJG-26-2758.pdf
Full Article (Word)	WJG-26-2758.docx
Manuscript File	53658-Review.docx
Answering Reviewers	53658-Answering reviewers.pdf
Audio Core Tip	53658-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	53658-Conflict-of-interest statement.pdf
Copyright License Agreement	53658-Copyright license agreement.PDF
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	53658-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	53658-Language certificate.pdf
Peer-review Report	53658-Peer-review(s).pdf
Scientific Misconduct Check	53658-Scientific misconduct check.pdf
Scientific Editor Work List	53658-Scientific editor work list.pdf
CrossCheck Report	53658-CrossCheck report.pdf