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Articles Published Processes
7/15/2020 11:47:34 AM | Browse: 887 | Download: 1474
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Received |
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2019-12-31 14:18 |
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Peer-Review Started |
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2019-12-31 14:18 |
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To Make the First Decision |
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Return for Revision |
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2020-05-05 19:22 |
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Revised |
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2020-05-17 05:50 |
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Second Decision |
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2020-06-16 08:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-06-17 20:14 |
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Articles in Press |
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2020-06-17 20:14 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-07-14 07:24 |
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Publish the Manuscript Online |
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2020-07-15 11:47 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Review |
Article Title |
Pancreatic neuroendocrine tumors G3 and pancreatic neuroendocrine carcinomas: differences in basic biology and treatment
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Manuscript Source |
Invited Manuscript |
All Author List |
Ming-Yi Zhang, Du He and Shuang Zhang |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Shuang Zhang, MD, PhD, Associate Professor, Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Gaopeng Street, Keyuan Road 4, Chengdu 610041, Sichuan Province, China. shuang.zhang@scu.edu.cn |
Key Words |
Neuroendocrine neoplasms; Pancreatic neuroendocrine tumors G3; Pancreatic neuroendocrine carcinomas; Gene sequencing; Clinical management; Histopathology |
Core Tip |
The major change in the 2017 World Health Organization (WHO) classification of pancreatic neuroendocrine neoplasms was to further subclassified the original G3 group into pancreatic neuroendocrine tumors G3 (pNETs G3) and pancreatic neuroendocrine carcinoma (pNEC). In 2019 this major change subsequently extended to neuroendocrine neoplasms involving the entire digestive tract. This review comprehensively summarizes the differences between pNET G3 and pNEC, which is the major update in latest WHO grading classification for pancreatic neuroendocrine neoplasms by the aspects of histology, gene mutation, and clinical management. |
Publish Date |
2020-07-15 11:47 |
Citation |
Zhang MY, He D, Zhang S. Pancreatic neuroendocrine tumors G3 and pancreatic neuroendocrine carcinomas: differences in basic biology and treatment. World J Gastrointest Oncol 2020; 12(7): 705-718 |
URL |
https://www.wjgnet.com/1948-5204/full/v12/i7/705.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v12.i7.705 |
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