| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
Do different bariatric surgical procedures influence plasma levels of matrix metalloproteinase-2, -7, and -9 among patients with type 2 diabetes mellitus?
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Wen-Chi Wu, Wei-Jei Lee, Tzong-His Lee, Shu-Chun Chen and Chih-Yen Chen |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Min-Sheng General Hospital, Taoyuan, and Far Eastern Memorial Hospital-National Yang-Ming University Joint Research Program |
105DN15 |
| Min-Sheng General Hospital, Taoyuan, and Far Eastern Memorial Hospital-National Yang-Ming University Joint Research Program |
106DN15 |
| Min-Sheng General Hospital, Taoyuan, and Far Eastern Memorial Hospital-National Yang-Ming University Joint Research Program |
107DN14 |
|
| Corresponding Author |
Chih-Yen Chen, AGAF, MD, PhD, Attending Doctor, Professor, Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, 201, Sec. 2, Shih-Pai Road, Taipei 11217, Taiwan. chency@vghtpe.gov.tw |
| Key Words |
Matrix metalloproteinases; Extracellular matrix; Obesity; Type 2 diabetes mellitus; Gastric bypass; Sleeve gastrectomy |
| Core Tip |
Bariatric surgery is a very effective strategy for managing obesity patients and those with type 2 diabetes mellitus. Matrix metalloproteinases play roles in extracellular matrix remodeling which consequently results in insulin resistance. Some authors reported higher levels of matrix metalloproteinases (MMP)-2, -7, and -9 in obese or diabetic patients. We measured plasma MMP-2, -7, and -9 concentrations in obese patients before and after bariatric surgeries; however, we did not identify any statistical differences in the MMP levels. We suggested that bariatric surgery reduces obesity and diabetes through MMP-2, -7, -9 independent pathways. |
| Publish Date |
2020-06-02 10:36 |
| Citation |
Wu WC, Lee WJ, Lee TH, Chen SC, Chen CY. Do different bariatric surgical procedures influence plasma levels of matrix metalloproteinase-2, -7, and -9 among patients with type 2 diabetes mellitus? World J Diabetes 2020; 11(6): 252-260 |
| URL |
https://www.wjgnet.com/1948-9358/full/v11/i6/252.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v11.i6.252 |
