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Articles Published Processes
5/25/2020 9:57:10 AM | Browse: 750 | Download: 1258
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Received |
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2020-01-12 13:34 |
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Peer-Review Started |
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2020-01-12 13:36 |
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To Make the First Decision |
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2020-02-28 03:59 |
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Return for Revision |
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2020-02-28 09:29 |
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Revised |
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2020-03-27 10:19 |
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Second Decision |
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2020-04-30 09:28 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-04-30 21:49 |
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Articles in Press |
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2020-04-30 21:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-05-17 10:38 |
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Publish the Manuscript Online |
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2020-05-25 09:57 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Review |
| Article Title |
Prophylactic and therapeutic roles of oleanolic acid its derivatives in several diseases
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Alaattin Sen |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Alaattin Sen, PhD, Academic Fellow, Academic Research, Chairman, Full Professor, Instructor, Research Scientist, Senior Lecturer, Senior Researcher, Senior Scientist, Department of Molecular Biology and Genetics, Faculty of Life and Natural Sciences, Abdullah Gul University, Sumer Campus, Kocasinan, Kayseri 38080, Türkiye. sena@agu.edu.tr |
| Key Words |
Oleanolic acid; Prophylactic; Anti-inflammatory; Anti-diabetics; Neuroprotective; Hepatoprotective |
| Core Tip |
Oleanolic acid (OA) is plentiful in many fruits and vegetables. Studies have shown that OA and its derivatives exert promising pharmacological actions including anti-inflammatory, neuroprotective, hepatoprotective, anti-osteoporotic and anti-diabetics at low doses. However, it is not a “cure-all” drug or drug candidate and could exert adverse effects at high doses, particularly its derivatives. In addition, information elucidating the drug-drug/drug-herb interactions associated with OA and its derivatives is inadequate. Nevertheless, there is a reasonable amount of literature, as fully explored in this review that OA and its derivatives have crucial prophylactic and therapeutic potential for diseases including ulcerative colitis, diabetes and cardiovascular diseases. |
| Publish Date |
2020-05-25 09:57 |
| Citation |
Sen A. Prophylactic and therapeutic roles of oleanolic acid its derivatives in several diseases. World J Clin Cases 2020; 8(10): 1767-1792 |
| URL |
https://www.wjgnet.com/2307-8960/full/v8/i10/1767.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v8.i10.1767 |
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