Publication Name	World Journal of Gastroenterology
Manuscript ID	5401
Country	China

Received	2013-09-09 09:07
Peer-Review Started	2013-09-09 16:56
To Make the First Decision	2013-09-27 16:54
Return for Revision	2013-09-29 10:31
Revised	2013-10-27 00:38
Second Decision	2014-01-08 18:21
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-08 18:30
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-17 14:09
Typeset the Manuscript	2014-04-01 11:00
Publish the Manuscript Online	2014-04-17 13:27

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Autobiography
Article Title	Caspase-3 expression in metastatic lymph nodes of esophageal squamous cell carcinoma is prognostic of survival
Manuscript Source	Invited Manuscript
All Author List	Xiu-Shen Wang, Kong-Jia Luo, Amos Ela Bella, Shan-Shan Bu, Jing Wen, Shui-Shen Zhang and Yi Hu
Funding Agency and Grant Number
Corresponding Author	Yi Hu, MD, PhD, Department of Thoracic Oncology, Cancer Center, Sun Yat-sen University, 651 Dong Feng Road East, Guangzhou 510080, Guangdong Province, China. huyi@sysucc.org.cn
Key Words	Esophageal squamous cell carcinoma; Caspase-3 protein; Prognosis; Lymph node
Core Tip	Reduced caspase-3 expression in primary esophageal squamous cell carcinoma (ESCC) is associated with poorer outcomes, but the prognostic value of caspase-3 in metastatic lymph nodes (MLNs) is unclear. Analysis of 122 patients with primary ESCCs and paired MLNs showed that higher caspase-3 expression in MLNs from ESCC was associated with poorer prognosis. To the best of our knowledge, this study is the first to report the potential prognostic value of caspase-3 expression in MLNs of ESCC. Additional studies are needed to assess the prognostic importance of this biomarker.
Publish Date	2014-04-17 13:27
Citation	Wang XS, Luo KJ, Bella AE, Bu SS, Wen J, Zhang SS, Hu Y. Caspase-3 expression in metastatic lymph nodes of esophageal squamous cell carcinoma is prognostic of survival. World J Gastroenterol 2014; 20(15): 4414-4420
URL	http://www.wjgnet.com/1007-9327/full/v20/i15/4414.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i15.4414

Full Article (PDF)	WJG-20-4414.pdf
Full Article (Word)	WJG-20-4414.doc
Manuscript File	5401-Review.doc
Answering Reviewers	5401-Answering reviewers.pdf
Copyright License Agreement	5401-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5401-Language certificate.pdf
Peer-review Report	5401-Peer review(s).pdf
Scientific Editor Work List	5401-Scientific editor work list.doc