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Articles Published Processes
5/29/2020 4:26:07 AM | Browse: 868 | Download: 1084
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Received |
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2020-01-10 16:31 |
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Peer-Review Started |
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2020-01-10 16:34 |
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To Make the First Decision |
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Return for Revision |
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2020-02-25 20:47 |
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Revised |
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2020-03-26 10:54 |
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Second Decision |
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2020-04-21 13:04 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-04-23 21:36 |
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Articles in Press |
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2020-04-23 21:36 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-05-15 07:53 |
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Typeset the Manuscript |
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2020-05-26 13:23 |
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Publish the Manuscript Online |
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2020-05-29 04:26 |
ISSN |
2220-3230 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Transplantation |
Manuscript Type |
Review |
Article Title |
Pharmacogenetics of immunosuppressant drugs: A new aspect for individualized therapy
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Manuscript Source |
Invited Manuscript |
All Author List |
Maurizio Salvadori and Aris Tsalouchos |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Maurizio Salvadori, MD, Professor, Department of Renal Transplantation, Careggi University Hospital, Viale Pieraccini 18, Florence 50139, Italy. maurizio.salvadori1@gmail.com |
Key Words |
Immunosuppressant pharmacokinetics; Immunosuppressant pharmacodynamics; Immunosuppressant pharmacogenetics; Immunosuppressant pharmacogenomics; Transplantation; Immunosuppressant drugs |
Core Tip |
The most common factors associated with drug response include age, sex, ancestry, concomitant drugs and liver or kidney diseases and drug pharmacogenetics. In general pharmacogenetics is the study of the variability of the response of a drug related to the complex of genes arrays. More recently, the term pharmacogenomics has been introduced. This term in particular is related to omics studies. In recent years, pharmacogenetics that evaluates the drug response to genetic variations has emerged as an important tool for choosing the right therapeutic dose. According to the aim of the Precision Medicare Initiative, pharmacogenomics may contribute to providing the right drug at the right dose for the right patient. |
Publish Date |
2020-05-29 04:26 |
Citation |
Salvadori M, Tsalouchos A. Pharmacogenetics of immunosuppressant drugs: A new aspect for individualized therapy. World J Transplant 2020; 10(5): 90-103 |
URL |
https://www.wjgnet.com/2220-3230/full/v10/i5/90.htm |
DOI |
https://dx.doi.org/ 10.5500/wjt.v10.i5.90 |
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