| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Non-invasive prediction of persistent villous atrophy in celiac disease
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Barbora Packova, Petra Kovalcikova, Zdenek Pavlovsky, Daniel Bartusek, Jitka Prokesova, Jiri Dolina and Radek Kroupa |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Ministry of Health, Czech Republic |
FNBr, 65269705 |
|
| Corresponding Author |
Radek Kroupa, MD, PhD, Doctor, Doctor, Research Assistant Professor, Department of Gastroenterology and Internal Medicine, University Hospital Brno, Faculty of Medicine, Masaryk University, Jihlavska 20, Brno 62500, Czech Republic. kroupa.radek@fnbrno.cz |
| Key Words |
Celiac disease; Villous atrophy; Anti-tissue transglutaminase antibodies; Anti-deamidated gliadin peptide antibodies; Abdominal ultrasound; Gluten-free diet |
| Core Tip |
We attempted to determine whether indicators such as anti-tissue transglutaminase antibodies (aTTG), anti-deamidated gliadin peptide antibodies (aDGP), and abdominal ultrasonography could predict villous atrophy (VA). We studied patients who were diagnosed with celiac disease and were on a gluten-free diet for at least one year; they were followed up for a maximum of four years. We determined that aTTG and aDGP were not optimal markers of persistent VA. However, we found that a combination of serology and bowel ultrasound examination enabled detection of VA with better accuracy. |
| Publish Date |
2020-07-14 15:42 |
| Citation |
Packova B, Kovalcikova P, Pavlovsky Z, Bartusek D, Prokesova J, Dolina J, Kroupa R. Non-invasive prediction of persistent villous atrophy in celiac disease. World J Gastroenterol 2020; 26(26): 3780-3791 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i26/3780.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i26.3780 |
