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Articles Published Processes
7/24/2020 1:08:23 PM | Browse: 897 | Download: 1262
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Received |
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2020-01-30 15:43 |
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Peer-Review Started |
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2020-01-30 15:44 |
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To Make the First Decision |
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Return for Revision |
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2020-04-18 22:20 |
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Revised |
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2020-06-03 08:22 |
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Second Decision |
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2020-06-10 08:48 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-06-10 19:49 |
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Articles in Press |
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2020-06-10 19:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-07-24 03:11 |
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Publish the Manuscript Online |
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2020-07-24 13:08 |
| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Review |
| Article Title |
MicroRNA sequences modulating inflammation and lipid accumulation in macrophage ‘foam’ cells: Implications for atherosclerosis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Richard James Lightbody, Janice Marie Walsh Taylor, Yvonne Dempsie and Annette Graham |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Heart Research UK |
RG2651 |
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| Corresponding Author |
Annette Graham, BSc, MA, PhD, Professor, Department of Biological and Biomedical Sciences, School of Health and Life Sciences, Glasgow Caledonian University, 70 Cowcaddens Road, Glasgow G4 0BA, United Kingdom. ann.graham@gcu.ac.uk |
| Key Words |
Coronary heart disease; Atherosclerosis; Macrophage ‘foam’ cell; Cholesterol; Inflammation; MicroRNA |
| Core Tip |
Micro-RNA (miRNA) sequences are short non-coding RNAs which play a key role in epigenetic regulation of gene transcription and translation. Significant changes in miRNA expression occur in macrophage ‘foam’ cells, laden with cholesterol and cholesteryl ester, which contribute not only to macrophage phenotype and inflammatory status, but also to novel pathways which may influence the development of atherosclerotic lesions, the principal underlying cause of coronary heart disease. The rapid expansion of this field of research is leading to new therapeutic targets and strategies for treatment of this progressive and highly complex global disease. |
| Publish Date |
2020-07-24 13:08 |
| Citation |
Lightbody RJ, Taylor JMW, Dempsie Y, Graham A. MicroRNA sequences modulating inflammation and lipid accumulation in macrophage ‘foam’ cells: Implications for atherosclerosis. World J Cardiol 2020; 12(7): 303-333 |
| URL |
https://www.wjgnet.com/1949-8462/full/v12/i7/303.htm |
| DOI |
https://dx.doi.org/10.4330/wjc.v12.i7.303 |
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