Publication Name	World Journal of Gastroenterology
Manuscript ID	5441
Country	Hungary

Received	2013-09-07 21:08
Peer-Review Started	2013-09-09 16:24
To Make the First Decision	2013-10-14 20:59
Return for Revision	2013-10-16 11:10
Revised
Second Decision	2014-01-15 20:10
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-15 20:24
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-04-23 09:46
Publish the Manuscript Online	2014-05-14 10:58

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Metabolic consequences of Helicobacter pylori infection and eradication
Manuscript Source	Invited Manuscript
All Author List	György Miklós Buzás
Funding Agency and Grant Number
Corresponding Author	Gyorgy Miklós Buzás, MD, PhD, Chief Gastroenterologist, Department of Gastroenterology, Ferencváros Health Centre, Mester utca 45, 1095 Budapest, Hungary. drbgym@gmail.com
Key Words	Diabetes mellitus; Cytokines; Glucose homeostasis; Growth; Helicobacter pylori; Interleukins; Lipid metabolism; Metabolic syndrome
Core Tip	Although Helicobacter pylori (H. pylori) in considered the main cause of peptic ulcer, gastric cancer and mucosa-associated lymphoid tissue lymphoma, the infection could induce many extragastric manifestations: among them, the metabolic disturbances are less well debated. Growth-as expression of general metabolism-could be delayed especially in low income-high infection prevalence regions and this can be restored by timely eradication of the infection. H. pylori infection may be associated with increased total and low density lipoprotein cholesterol and decrease of high density liporotein, creating an atherogenic lipid profile and promoting atherosclerosis. H. pylori is consistently associated with insulin resistance. In the future, larg-scale studies are needed to clarify if eradication of H. pylori will result in restoration of normal growth, decrease of atherosclerotic disease, type 2 diabetes mellitus and metabolic syndrome.
Publish Date	2014-05-14 10:58
Citation	Buzás GM. Metabolic consequences of Helicobacter pylori infection and eradication. World J Gastroenterol 2014; 20(18): 5226-5234
URL	http://www.wjgnet.com/1007-9327/full/v20/i18/5226.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i18.5226

Full Article (PDF)	WJG-20-5226.pdf
Full Article (Word)	WJG-20-5226.doc
Manuscript File	5441-Review.doc
Answering Reviewers	5441-Answering reviewers.pdf
Copyright License Agreement	5441-Copyright assignment.pdf
Peer-review Report	5441-Peer review(s).pdf
Scientific Editor Work List	5441-Scientific editor work list.doc