ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Clinical and Translational Research |
Article Title |
Clinicopathological features of early gastric cancers arising in Helicobacter pylori uninfected patients
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Chiko Sato, Kingo Hirasawa, Yoko Tateishi, Yuichiro Ozeki, Atsushi Sawada, Ryosuke Ikeda, Takehide Fukuchi, Masafumi Nishio, Ryosuke Kobayashi, Makomo Makazu, Hiroaki Kaneko, Yoshiaki Inayama and Shin Maeda |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Kingo Hirasawa, MD, PhD, Associate Professor, Chief Doctor, Endoscopy Division, Yokohama City University Medical Center, 4-57, Urafune-cho, Minami-ku, Yokohama 232-0024, Kanagawa, Japan. kingo_h@yokohama-cu.ac.jp |
Key Words |
Early gastric cancer; Helicobacter pylori; Un-infection; Negative; Clinicopathological features; Endoscopic submucosal dissection |
Core Tip |
Chronic helicobacter pylori (H. pylori) infection is a major risk factor for gastric cancer. Historically, gastric cancers in Japan were related to H. pylori infection, and the frequency of H. pylori uninfected gastric cancer (HpUIGC) was very rare. However, the rarity of gastric cancer in H. pylori negative patients may be partly owing to underreporting, and the mechanisms behind the development and progression of this type of gastric cancer must be elucidated. This study elucidated the clinicopathological features of H. pylori uninfected gastric cancer from 30 gastric cancer patients. Differentiated-type gastric cancers without submucosal invasion were most prominent. |
Publish Date |
2020-05-28 13:08 |
Citation |
Sato C, Hirasawa K, Tateishi Y, Ozeki Y, Sawada A, Ikeda R, Fukuchi T, Nishio M, Kobayashi R, Makazu M, Kaneko H, Inayama Y, Maeda S. Clinicopathological features of early gastric cancers arising in Helicobacter pylori uninfected patients. World J Gastroenterol 2020; 26(20): 2618-2631 |
URL |
https://www.wjgnet.com/1007-9327/full/v26/i20/2618.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v26.i20.2618 |