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Articles Published Processes
5/14/2020 10:35:45 AM | Browse: 772 | Download: 998
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Received |
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2020-02-03 20:58 |
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Peer-Review Started |
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2020-02-03 20:58 |
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To Make the First Decision |
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Return for Revision |
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2020-02-25 20:13 |
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Revised |
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2020-04-14 21:42 |
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Second Decision |
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2020-04-23 07:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-04-25 14:21 |
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Articles in Press |
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2020-04-25 14:21 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-05-13 00:05 |
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Publish the Manuscript Online |
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2020-05-14 10:35 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Neutropenia in colorectal cancer treated with oxaliplatin-based hyperthermic intraperitoneal chemotherapy: An observational cohort study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Peter H Cashin, Lana Ghanipour, Malin Enblad and David L Morris |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Peter H Cashin, MD, PhD, Director, Surgeon, Department of Surgical Sciences, Uppsala University, Akademiska sjukhuset, Uppsala 75185, Sweden. peter.cashin@surgsci.uu.se |
| Key Words |
Colorectal cancer; Peritoneal metastases; Cytoreductive surgery; Hyperthermic intraperitoneal chemotherapy; Oxaliplatin; Neutropenia |
| Core Tip |
We investigated neutropenia after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) treatment of colorectal cancer with peritoneal metastases. The frequency of neutropenia was 13%; however, it was much more common in the oxaliplatin + irinotecan HIPEC treatment than in the single oxaliplatin HIPEC treatment. Neutropenia did not increase the risk of Clavien-Dindo morbidity. Furthermore, it was found to be an independent prognostic factor for disease-free survival. In conclusion, we found that neutropenia doesn’t appear to be a toxicity limiting factor as it does not increase the postoperative morbidity, but rather a positive prognostic factor that may predict a better outcome. |
| Publish Date |
2020-05-14 10:35 |
| Citation |
Cashin PH, Ghanipour L, Enblad M, Morris DL. Neutropenia in colorectal cancer treated with oxaliplatin-based hyperthermic intraperitoneal chemotherapy: An observational cohort study. World J Gastrointest Oncol 2020; 12(5): 549-558 |
| URL |
https://www.wjgnet.com/1948-5204/full/v12/i5/549.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v12.i5.549 |
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