Publication Name	World Journal of Gastroenterology
Manuscript ID	5457
Country	United States

Received	2013-09-09 11:23
Peer-Review Started	2013-09-11 16:07
To Make the First Decision	2013-10-22 16:51
Return for Revision	2013-10-22 18:11
Revised	2013-11-07 02:37
Second Decision	2013-11-29 11:22
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-11-30 01:26
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-01-06 09:53
Publish the Manuscript Online	2014-01-20 17:10

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Immunopathology of inflammatory bowel disease
Manuscript Source	Invited Manuscript
All Author List	Kori L Wallace, Li-Bo Zheng, Yoshitake Kanazawa and David Q Shih
Funding Agency and Grant Number	Funding Agency Grant Number NIH KO8 DK093578 CCFA Career Development Award 3467 (DQS) F Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute
Corresponding Author	David Q Shih, MD, PhD, F Widjaja Foundation, Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Suite 4066, Los Angeles CA 90048, United States. david.shih@csmc.edu
Key Words	Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis; Microbiome; Autophagy; T helper 17; Innate immune system; Adaptive immune system; Innate lymphoid cells; TL1A
Core Tip	Inflammatory bowel disease (IBD) results from the complex interactions between susceptibility genes, the environment, the immune system, and the host’s microbiome. It is thought that either a mucosal susceptibility or a defect in sampling of gut luminal antigen leads to activation of the innate immune system that then recruits cells of the adaptive immune system leading to inflammation. This review will detail the interaction of these components in the immunopathogenesis of IBD.
Publish Date	2014-01-20 17:10
Citation	Wallace KL, Zheng LB, Kanazawa Y, Shih DQ. Immunopathology of inflammatory bowel disease. World J Gastroenterol 2014; 20(1): 6-21
URL	http://www.wjgnet.com/1007-9327/full/v20/i1/6.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i1.6

Manuscript File	5457-Review.doc
Answering Reviewers	5457-Answering reviewers.pdf
Copyright License Agreement	5457-Copyright assignment.pdf
Peer-review Report	5457-Peer review(s).pdf
Scientific Editor Work List	5457-Scientific editor work list.doc