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Articles Published Processes
6/25/2020 10:09:17 AM | Browse: 849 | Download: 1173
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Received |
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2020-02-21 07:24 |
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Peer-Review Started |
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2020-02-21 07:25 |
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To Make the First Decision |
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Return for Revision |
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2020-03-30 16:33 |
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Revised |
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2020-04-24 13:23 |
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Second Decision |
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2020-05-11 12:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-05-12 23:05 |
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Articles in Press |
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2020-05-12 23:05 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-05-20 00:16 |
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Typeset the Manuscript |
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2020-06-23 19:11 |
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Publish the Manuscript Online |
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2020-06-25 10:09 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Retrospective Study |
| Article Title |
High tibial osteotomy with human umbilical cord blood-derived mesenchymal stem cells implantation for knee cartilage regeneration
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jun-Seob Song, Ki-Taek Hong, Chae-Gwan Kong, Na-Min Kim, Jae-Yub Jung, Han-Soo Park, Young Ju Kim, Ki Bong Chang and Seok Jung Kim |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Seok Jung Kim, FRCS, MD, PhD, Director, Director, Professor, Surgeon, Department of Orthopedic Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 271, Cheonbo-ro, Uijeongbu-si 11765, Gyeonggi-do, South Korea. peter@catholic.ac.kr |
| Key Words |
Allogeneic; Human umbilical cord blood-derived mesenchymal stem cells; Cartilage regeneration; High tibial osteotomy; Osteoarthritic knees; Arthroscopy |
| Core Tip |
This is the first study to evaluate clinical outcomes and cartilage regeneration via second-look arthroscopy after implantation of human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) with concomitant high tibial osteotomy (HTO) for treatment of osteoarthritic knee with varus deformity. HTO treatment of medial compartment osteoarthritis of the knee with varus deformity alone does not sufficiently repair arthritic joints. However, HTO decreases pressure in the medial compartment, providing an environment in which damaged cartilage can be regenerated via implantation of allogenic hUCB-MSCs. hUCB-MSC implantation with HTO is an effective treatment for patients with osteoarthritis of the knee with varus deformity, leading to improved clinical outcomes. |
| Publish Date |
2020-06-25 10:09 |
| Citation |
Song JS, Hong KT, Kong CG, Kim NM, Jung JY, Park HS, Kim YJ, Chang KB, Kim SJ. High tibial osteotomy with human umbilical cord blood-derived mesenchymal stem cells implantation for knee cartilage regeneration. World J Stem Cells 2020; 12(6): 514-526 |
| URL |
https://www.wjgnet.com/1948-0210/full/v12/i6/514.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v12.i6.514 |
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