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9/4/2014 3:52:00 PM | Browse: 428 | Download: 236
Publication Name World Journal of Gastroenterology
Manuscript ID 5477
Country of Manuscript Source Germany
Received
2013-09-10 11:23
Peer-Review Started
2013-09-11 20:01
To Make the First Decision
2013-10-22 16:48
Return for Revision
2013-10-23 09:39
Revised
2013-11-12 04:56
Second Decision
2013-11-29 11:23
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-11-30 01:27
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-01-10 14:56
Publish the Manuscript Online
2014-01-19 14:17
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Topic Highlights
Article Title Diagnostic utility of faecal biomarkers in patients with irritable bowel syndrome
Manuscript Source Invited Manuscript
All Author List Jan Däbritz, Jason Musci and Dirk Foell
Funding Agency and Grant Number
Funding Agency Grant Number
German Research Foundation DFG DA1161/5-1 (to Däbritz J)
Corresponding author Dirk Foell, MD, Professor, Director, Department of Paediatric Rheumatology and Immunology, University Children’s Hospital Münster, Röntgenstr. 21, 48149 Münster, Germany. dfoell@uni-muenster.de
Keywords S100A12; Calprotectin; Lactoferrin; M2-pyruvate kinase; Polymorphonuclear elastase; Defensins; Granins; Irritable bowel syndrome
Core Tip Faecal markers of intestinal inflammation represent a practicable, non-invasive, inexpensive and objective diagnostic tool to differentiate organic [inflammatory bowel disease (IBD)] and functional [irritable bowel syndrome (IBS)] gastrointestinal diseases. Faecal markers have the potential to be incorporated into standard clinical practice for the routine assessment of IBS and IBD. Neutrophil-derived faecal biomarkers show a high diagnostic accuracy in the differentiation of IBD vs IBS. They can provide reassurance to the physicians that the clinical diagnosis of IBS is correct. Future progress in our knowledge about the biology of these proteins and the underlying pathogenesis of IBS will help translate IBD/IBS research into patient care.
Publish Date 2014-01-19 14:17
Citation D?britz J, Musci J, Foell D. Diagnostic utility of faecal biomarkers in patients with irritable bowel syndrome. World J Gastroenterol 2014; 20(2): 363-375
Url http://www.wjgnet.com/1007-9327/full/v20/i2/363.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i2.363
Full Article (PDF) WJG-20-363.pdf
Full Article (Word) WJG-20-363.doc
Manuscript File 5477-Review.docx
Answering Reviewers 5477-Answering reviewers.pdf
Copyright License Agreement 5477-Copyright assignment.pdf
Peer-review Report 5477-Peer review(s).pdf
Scientific Editor Work List 5477-Scientific editor work list.doc