Publication Name	World Journal of Gastroenterology
Manuscript ID	5477
Country	Germany

Received	2013-09-10 11:23
Peer-Review Started	2013-09-11 20:01
To Make the First Decision	2013-10-22 16:48
Return for Revision	2013-10-23 09:39
Revised	2013-11-12 04:56
Second Decision	2013-11-29 11:23
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-11-30 01:27
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-01-10 14:56
Publish the Manuscript Online	2014-01-19 14:17

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Diagnostic utility of faecal biomarkers in patients with irritable bowel syndrome
Manuscript Source	Invited Manuscript
All Author List	Jan Däbritz, Jason Musci and Dirk Foell
Funding Agency and Grant Number	Funding Agency Grant Number German Research Foundation DFG DA1161/5-1 (to Däbritz J)
Corresponding Author	Dirk Foell, MD, Professor, Director, Department of Paediatric Rheumatology and Immunology, University Children’s Hospital Münster, Röntgenstr. 21, 48149 Münster, Germany. dfoell@uni-muenster.de
Key Words	S100A12; Calprotectin; Lactoferrin; M2-pyruvate kinase; Polymorphonuclear elastase; Defensins; Granins; Irritable bowel syndrome
Core Tip	Faecal markers of intestinal inflammation represent a practicable, non-invasive, inexpensive and objective diagnostic tool to differentiate organic [inflammatory bowel disease (IBD)] and functional [irritable bowel syndrome (IBS)] gastrointestinal diseases. Faecal markers have the potential to be incorporated into standard clinical practice for the routine assessment of IBS and IBD. Neutrophil-derived faecal biomarkers show a high diagnostic accuracy in the differentiation of IBD vs IBS. They can provide reassurance to the physicians that the clinical diagnosis of IBS is correct. Future progress in our knowledge about the biology of these proteins and the underlying pathogenesis of IBS will help translate IBD/IBS research into patient care.
Publish Date	2014-01-19 14:17
Citation	D?britz J, Musci J, Foell D. Diagnostic utility of faecal biomarkers in patients with irritable bowel syndrome. World J Gastroenterol 2014; 20(2): 363-375
URL	http://www.wjgnet.com/1007-9327/full/v20/i2/363.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i2.363

Full Article (PDF)	WJG-20-363.pdf
Full Article (Word)	WJG-20-363.doc
Manuscript File	5477-Review.docx
Answering Reviewers	5477-Answering reviewers.pdf
Copyright License Agreement	5477-Copyright assignment.pdf
Peer-review Report	5477-Peer review(s).pdf
Scientific Editor Work List	5477-Scientific editor work list.doc