Publication Name	World Journal of Gastroenterology
Manuscript ID	5478
Country	China

Received	2013-09-10 11:29
Peer-Review Started	2013-09-11 20:13
To Make the First Decision	2013-10-14 20:56
Return for Revision	2013-10-18 17:39
Revised	2013-11-10 23:01
Second Decision	2014-01-15 20:10
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-15 20:25
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-02-28 20:38
Typeset the Manuscript	2014-03-28 16:19
Publish the Manuscript Online	2014-04-17 13:27

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Autobiography
Article Title	Expression of monocyte chemotactic protein-1/CCL2 in gastric cancer and its relationship with tumor hypoxia
Manuscript Source	Invited Manuscript
All Author List	Lei-Lei Tao, Shu-Jing Shi, Long-Bang Chen and Gui-Chun Huang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81101739 China International Medical Foundation CIMF-F-H001-023
Corresponding Author	Gui-Chun Huang, MD, PhD, Medical Oncology Department of Jinling Hospital, Medical School of Nanjing University, 305 ZhongShan Eastern Road, Nanjing 210002, Jiangsu Province, China. huangguichun@nju.edu.cn
Key Words	Chemokines; Monocyte chemotactic protein-1/CCL2; Gastric cancer; Prognostic marker; Immunohistochemistry
Core Tip	The authors have performed immunohistochemical analysis of CCL2 and hypoxia-inducible factor 1 alpha (HIF-1α) in consecutive formalin-fixed paraffin-embedded sections of 68 gastric tumor samples taken from gastric cancer patients. The expression of the monocyte chemotactic protein-1/CCL2 is associated with the expression of HIF-1α. The research results showed a correlation between the expression of both proteins in gastric carcinoma. The authors have statistically analyzed the relationship of CCL2 expression with the clinicopathological characteristics of the patients and their survival time. The expression of CCL2 could be used as a prognostic biomarker for gastric cancer.
Publish Date	2014-04-17 13:27
Citation	Tao LL, Shi SJ, Chen LB, Huang GC. Expression of monocyte chemotactic protein-1/CCL2 in gastric cancer and its relationship with tumor hypoxia. World J Gastroenterol 2014; 20(15): 4421-4427
URL	http://www.wjgnet.com/1007-9327/full/v20/i15/4421.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i15.4421

Full Article (PDF)	WJG-20-4421.pdf
Full Article (Word)	WJG-20-4421.doc
Manuscript File	5478-Review.doc
Answering Reviewers	5478-Answering reviewers.pdf
Copyright License Agreement	5478-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5478-Language certificate.pdf
Peer-review Report	5478-Peer review(s).pdf
Scientific Editor Work List	5478-Scientific editor work list.doc