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6/15/2020 8:19:14 AM | Browse: 798 | Download: 977
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 54885
Country/Territory Canada
Received
2020-02-24 16:53
Peer-Review Started
2020-02-24 16:54
To Make the First Decision
Return for Revision
2020-04-09 20:54
Revised
2020-05-08 07:25
Second Decision
2020-05-28 09:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-05-29 20:29
Articles in Press
2020-05-29 20:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-06-12 01:52
Publish the Manuscript Online
2020-06-15 08:19
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Review
Article Title Real-world evidence on adjuvant chemotherapy in older adults with stage II/III colon cancer
Manuscript Source Invited Manuscript
All Author List Atul Batra, Rodrigo Rigo, Dropen Sheka and Winson Y Cheung
ORCID
Author(s) ORCID Number
Atul Batra http://orcid.org/0000-0002-1934-8408
Rodrigo Rigo http://orcid.org/0000-0002-4188-0329
Dropen Sheka http://orcid.org/0000-0002-7050-0794
Winson Y Cheung http://orcid.org/0000-0002-3679-4290
Funding Agency and Grant Number
Corresponding Author Winson Y Cheung, MD, Doctor, Professor, Department of Oncology, University of Calgary, 1331 – 29 Street NW, Calgary T2N 4N2, Alberta, Canada. winson.cheung@ahs.ca
Key Words Colon cancer; Older adults; Adjuvant chemotherapy; Real-world evidence; ;
Core Tip Use of adjuvant chemotherapy consisting of fluoropyrimidines with/without oxaliplatin has improved survival outcomes for patients with resected colon cancer, especially in those with stage III disease. However, older adults are often not given the opportunity to benefit from chemotherapy after surgery because undertreatment may occur due to various patient and physician related factors. The issue is further compounded by the limited representation of older adults in clinical trials, resulting in underpowered subgroup analyses that do not provide conclusive answers regarding the utility of adjuvant chemotherapy in the advanced age group. We herein review the role of adjuvant chemotherapy in early stage colon cancer, specifically in the context of the older subpopulation, by focusing on both data from clinical trials and data from real-world evidence sources.
Publish Date 2020-06-15 08:19
Citation Batra A, Rodrigo R, Sheka D, Cheung WY. Real-world evidence on adjuvant chemotherapy in older adults with stage II/III colon cancer. World J Gastrointest Oncol 2020; 12(6): 604-618
URL https://www.wjgnet.com/1948-5204/full/v12/i6/604.htm
DOI https://dx.doi.org/10.4251/wjgo.v12.i6.604
Full Article (PDF) WJGO-12-604.pdf
Full Article (Word) WJGO-12-604.docx
Manuscript File 54885-Review.docx
Answering Reviewers 54885-Answering reviewers.pdf
Audio Core Tip 54885-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 54885-Conflict-of-interest statement.pdf
Copyright License Agreement 54885-Copyright license agreement.pdf
Peer-review Report 54885-Peer-review(s).pdf
Scientific Misconduct Check 54885-Bing-Tang JZ-1.png
Scientific Misconduct Check 54885-Scientific misconduct check.pdf
Scientific Editor Work List 54885-Scientific editor work list.pdf