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Articles Published Processes
6/15/2020 8:19:14 AM | Browse: 925 | Download: 1411
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Received |
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2020-02-24 16:53 |
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Peer-Review Started |
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2020-02-24 16:54 |
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To Make the First Decision |
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Return for Revision |
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2020-04-09 20:54 |
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Revised |
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2020-05-08 07:25 |
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Second Decision |
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2020-05-28 09:32 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-05-29 20:29 |
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Articles in Press |
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2020-05-29 20:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-06-12 01:52 |
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Publish the Manuscript Online |
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2020-06-15 08:19 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Real-world evidence on adjuvant chemotherapy in older adults with stage II/III colon cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Atul Batra, Rodrigo Rigo, Dropen Sheka and Winson Y Cheung |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Winson Y Cheung, MD, Doctor, Doctor, Professor, Department of Oncology, University of Calgary, 1331 – 29 Street NW, Calgary T2N 4N2, Alberta, Canada. winson.cheung@ahs.ca |
| Key Words |
Colon cancer; Older adults; Adjuvant chemotherapy; Real-world evidence; ; |
| Core Tip |
Use of adjuvant chemotherapy consisting of fluoropyrimidines with/without oxaliplatin has improved survival outcomes for patients with resected colon cancer, especially in those with stage III disease. However, older adults are often not given the opportunity to benefit from chemotherapy after surgery because undertreatment may occur due to various patient and physician related factors. The issue is further compounded by the limited representation of older adults in clinical trials, resulting in underpowered subgroup analyses that do not provide conclusive answers regarding the utility of adjuvant chemotherapy in the advanced age group. We herein review the role of adjuvant chemotherapy in early stage colon cancer, specifically in the context of the older subpopulation, by focusing on both data from clinical trials and data from real-world evidence sources. |
| Publish Date |
2020-06-15 08:19 |
| Citation |
Batra A, Rodrigo R, Sheka D, Cheung WY. Real-world evidence on adjuvant chemotherapy in older adults with stage II/III colon cancer. World J Gastrointest Oncol 2020; 12(6): 604-618 |
| URL |
https://www.wjgnet.com/1948-5204/full/v12/i6/604.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v12.i6.604 |
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