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Articles Published Processes
6/8/2020 3:14:59 AM | Browse: 808 | Download: 1333
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Received |
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2020-02-27 02:31 |
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Peer-Review Started |
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2020-02-27 02:31 |
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To Make the First Decision |
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Return for Revision |
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2020-04-29 22:31 |
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Revised |
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2020-05-13 06:54 |
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Second Decision |
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2020-05-22 09:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-05-23 00:51 |
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Articles in Press |
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2020-05-23 00:51 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-06-02 01:18 |
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Publish the Manuscript Online |
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2020-06-08 03:14 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Minireviews |
| Article Title |
Altered physiology of mesenchymal stem cells in the pathogenesis of adolescent idiopathic scoliosis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Dai Sik Ko, Yun Hak Kim, Tae Sik Goh and Jung Sub Lee |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Research Foundation of Korea |
NRF-2020R1C1C1003741 |
| National Research Foundation of Korea |
NRF-2018R1D1A1B07047666 |
| National Research Foundation of Korea |
NRF-2017M3C9A6047610 |
| Biomedical Research Institute |
Research council 2020 |
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| Corresponding Author |
Tae Sik Goh, MD, PhD, Doctor, Doctor, Surgeon, Orthopaedic Surgery, Pusan National University Hospital, 179 Gudeok-ro, Busan 49241, South Korea. taesikgoh@gmail.com |
| Key Words |
Adolescent idiopathic scoliosis; Mesenchymal stem cell; Bioinformatics; Transcriptome; Proteome; |
| Core Tip |
Adolescent idiopathic scoliosis (AIS) is a common spinal deformity that occurs in adolescent females. Despite many reports, the pathomechanism of this disease is still unclear. Mesenchymal Stem Cells (MSCs) that differentiate into multiple cell lineages are known to contribute to the initiation and progression of AIS, but the exact role has not been understood yet. In this review, we summarize a series of studies on the role of mesenchymal stem cells, with differential expression levels of gene, RNA, and protein, in the pathogenesis of AIS. Furthermore, we present the future perspectives on the role of MSCs in the clinical outcome of AIS. |
| Publish Date |
2020-06-08 03:14 |
| Citation |
Ko DS, Kim YH, Goh TS, Lee JS. Altered physiology of mesenchymal stem cells in the pathogenesis of adolescent idiopathic scoliosis. World J Clin Cases 2020; 8(11): 2102-2110 |
| URL |
https://www.wjgnet.com/2307-8960/full/v8/i11/2102.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v8.i11.2102 |
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